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Antimicrobial Activity of Ethylenediaminedisuccinate Metal Complexes
(WILEY-V C H VERLAG GMBH, 2008)
It is shown that metal complexes of the biodegradable ligand ethylenediaminedisuccinic acid (edds) present antimicrobial activity towards fungi and bacteria. [Cd(edds)], in particular, is more toxic than free Cd2+ to ...
The need to unmask lurking false friends: sustainability is a state, not a process!
(Associação Brasileira de Ciência Ecológica e Conservação, 2013-07)
Monjeau (2010, p. 117) concluded that “a possible way out from conservation crossroads might consist in being able to distinguish friends from dangerous enemies” and that conservation in Latin America is “full of Trojan ...
Antibacterial and antitumorigenic properties of microcin E492, a poreforming bacteriocin
(2009)
Microcins are a family of low-molecular weight bacteriocins produced and secreted by Gram-negative bacteria. This review is focused on microcin E492, a pore-forming bacteriocin produced by Klebsiella pneumoniae RYC492 that ...
Botulinum neurotoxin: Evolution from poison, to research tool - Onto medicinal therapeutic and future pharmaceutical panacea
(2007)
Botulinum neurotoxin (BoNT), for more than a hundred years, has been a recognized poisonous principle in spoiled food. As its chemical structure became unraveled, and as more knowledge was gained over its mechanism of ...
NTS-Polyplex: a potential nanocarrier for neurotrophic therapy of Parkinson's disease
(2012)
Nanomedicine has focused on targeted neurotrophic gene delivery to the brain as a strategy to stop and reverse neurodegeneration in Parkinson's disease. Because of improved transfection ability, synthetic nanocarriers have ...
A motogenic gabaergic system of mononuclear phagocytes facilitates dissemination of coccidian parasites
(2020-10)
Gamma-aminobutyric acid (GABA) serves diverse biological functions in prokaryotes and eukaryotes, including neurotransmission in vertebrates. Yet, the role of GABA in the immune system has remained elusive. Here, a ...
A "Trojan horse" strategy to reverse drug-resistance in brain tumors
(Universidad del RosarioDoctorado en Ciencias BiomédicasFacultad de Ciencias Naturales y Matemáticas, 2014)
Malignant gliomas represent one of the most aggressive forms of Central Nervous System
(CNS) tumors. According to the WHO classification of brain tumors, astrocytomas have been
categorized into four grades, determined ...
The association of statins plus LDL receptor-targeted liposome-encapsulated doxorubicin increases in vitro drug delivery across blood-brain barrier cells
Background and PurposeThe passage of drugs across the blood-brain barrier (BBB) limits the efficacy of chemotherapy in brain tumours. For instance, the anticancer drug doxorubicin, which is effective against glioblastoma ...