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A INFLUÊNCIA DA MODULAÇÃO POR TLR2, TLR4 E TLR9 NA RESPOSTA DE CÉLULAS T REGULADORAS EM CULTURA DE SANGUE PERIFÉRICO DE INDIVÍDUOS COM INFECÇÃO LATENTE PELO Mycobacterium tuberculosis, DESAFIADAS IN VITRO COM O BACILO DE KOCH.
(Universidade Federal do Espírito SantoBRPrograma de Pós-Graduação em Doenças InfecciosasUFESDoutorado em Doenças Infecciosas, 2018-07-10)
A infecção latente por Mycobacterium tuberculosis (LTBI) afeta aproximadamente um quarto da população mundial. Durante a LTBI, o M. tuberculosis (Mtb) sobrevive num estado de dormência, que na reativação da infecção latente, ...
Activation of TLR2 and TLR4 by glycosylphosphatidylinositols derived from Toxoplasma gondii
(American Association of Immunologists, 2022)
Expression and activation of intracellular receptors TLR7, TLR8 and TLR9 in peripheral blood monocytes from HIV-infected patients.
(2013-07-09)
Introduction. TLR´s play a role in host defense in HIV infection
recognizing the viral DNA or RNA. Their activation induces a signaling
pathway that includes the proteins MyD88, IRAK4, TRAF6 and
the transcription factor ...
Impaired Innate Immunity in Tlr4(-/-) Mice but Preserved CD8(+) T Cell Responses against Trypanosoma cruzi in Tlr4-, Tlr2-, Tlr9- or Myd88-Deficient Mice
(PUBLIC LIBRARY SCIENCE, 2010)
The murine model of T. cruzi infection has provided compelling evidence that development of host resistance against intracellular protozoans critically depends on the activation of members of the Toll-like receptor (TLR) ...
Absence of functional TLR4 impairs response of macrophages after Candida albicans infection
(TAYLOR & FRANCIS LTD, 2010)
Candida albicans is recognized by phagocytic cells through a set of recognition receptors patterns. Recently, we showed the importance of TLR2 in the regulation of neutrophil survival after C. albicans infection. In the ...
Immune Response Against Sporothrix schenckii in TLR-4-Deficient Mice
(Springer, 2012-07-01)
For many fungal diseases, macrophages are the major cell population implicated in host protection, primarily by their ability to eliminate the invading fungal pathogen through phagocytosis. In sporotrichosis, this remains ...
Immune Response Against Sporothrix schenckii in TLR-4-Deficient Mice
(Springer, 2012-07-01)
For many fungal diseases, macrophages are the major cell population implicated in host protection, primarily by their ability to eliminate the invading fungal pathogen through phagocytosis. In sporotrichosis, this remains ...
Participation of TLR2 and TLR4 in Cytokines Production by Patients with Symptomatic and Asymptomatic Chronic Chagas Disease
(2017-01-01)
Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is a serious public health issue. Its evolution involves an acute stage, characterized by no specific symptoms, and the chronic stage during most individuals ...
TLR2-dependent mast cell activation contributes to the control of Mycobacterium tuberculosis infection
(ELSEVIER SCIENCE BV, 2009)
Mast Cells (MCs) express toll-like receptor 2 (TLR2), a receptor known to be triggered by several major mycobacterial ligands and involved in resistance against Mycobacterium tuberculosis (MTB) infection. This study ...