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Direct thrombin inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in people with non-valvular atrial fibrillation
(Wiley, 2014)
BACKGROUND: Chronic anticoagulation with vitamin K antagonists (VKAs) prevents ischaemic stroke and systemic embolism in people with non-valvular atrial fibrillation (AF) but dose adjustment, coagulation monitoring and ...
Advances in sickle cell disease treatment: From drug discovery until the patient monitoring
(2011-04-01)
Sickle Cell Disease (SCD) is one of the most prevalent hematological diseases in the world. Despite the immense progress in molecular knowledge about SCD in last years few therapeutical sources are currently available. ...
Advances in sickle cell disease treatment: From drug discovery until the patient monitoring
(2011-04-01)
Sickle Cell Disease (SCD) is one of the most prevalent hematological diseases in the world. Despite the immense progress in molecular knowledge about SCD in last years few therapeutical sources are currently available. ...
Applications of Nanosystems to Anticancer Drug Therapy (Part I. Nanogels, Nanospheres, Nanocapsules)
(Bentham Science Publishers, 2014)
One of the greatest challenges in cancer drug therapy is to maximize the effectiveness of the active agent while reducing its systemic adverse effects. To add more, many widely-used chemoterapeutic agents present unfavorable ...
Administration and therapeutic drug monitoring of β-lactams 2 and vancomycin in critical care units in Colombia : The ANTI- 3 BIOCOL study
(Universidad de La Sabana, 2021-08-11)
Therapeutic Drug Monitoring (TDM) and continuous infusion strategies are effec- 15 tive interventions in clinical practice, but these practices are little still unknown in Colombia, 16 especially in the critical care ...
Is There a Role for the Therapeutic Drug Monitoring of Colistin? An Overview¿Tiene alguna función la monitorización terapéutica de los fármacos colistina? Una descripción general
(Pharmaceuticals, 2020)
Colistin is used as a last-line antibiotic for the treatment of Gram-negative multiresistant bacteria. Due to its high nephrotoxicity, Therapeutic Drug Monitoring (TDM) is recommended for dose adjustment. We aimed to ...
Solid phase microextraction chemical biopsy tool for monitoring of doxorubicin residue during in vivo lung chemo-perfusion
(Elsevier, 2021-02)
Development of a novel in vivo lung perfusion (IVLP) procedure allows localized delivery of high-dose doxorubicin (DOX) for targeting residual micrometastatic disease in the lungs. However, DOX delivery via IVLP requires ...
Pharmacoepidemiology of tacrolimus in pediatric liver transplantation
(Wiley Blackwell Publishing, Inc, 2017-08)
AEs during immunosuppressive treatment with tacrolimus are very common. We retrospectively evaluated FK safety and efficacy in a large pediatric liver transplant cohort in Latin America. During 2-year follow-up, we analyzed ...
Análise simultânea da losartana, metformina e sinvastatina por cromatografia líquida
(DFA - Departamento de Farmácia – São Cristóvão - PresencialUniversidade Federal de Sergipe, 2022)