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DIRECTED EVOLUTION OF ENZYMES: SMALL CHANGES, BETTER BIOCATALYSTS
(Soc Brasileira Quimica, 2020-06-01)
Biocatalysis is now a mature field, both in the laboratory and industrial scale. This approach counts on enzyme high selectivity, biodegradability, elegant control over the outcome of reaction conditions and as a possible ...
Synthesis, cytotoxicity and in vitro antileishmanial activity of naphthothiazoles
(2013-06-01)
The leishmaniasis is a spectral disease caused by the protozoan Leishmania spp., which threatens millions of people worldwide. Current treatments exhibit high toxicity, and there is no vaccine available. The need for new ...
Selective Semi-Hydrogenation of Terminal Alkynes Promoted by Bimetallic Cu-Pd Nanoparticles
(Georg Thieme Verlag Kg, 2018-11)
The selective semi-hydrogenation of terminal alkynes was efficiently performed, under mild reaction conditions (H 2 balloon, 110 °C), promoted by a bimetallic nanocatalyst composed of copper and palladium nanoparticles ...
A Role for Insulin on L-Arginine Transport in Fetal Endothelial Dysfunction in Hyperglycaemia
(BENTHAM SCIENCE PUBL LTD, 2009)
Endothelial cells are key in the regulation of vascular tone through the release of vasoactive molecules, including nitric oxide (NO). NO is a gas synthesized from the cationic amino acid L-arginine via the endothelial NO ...
Obtenção de derivados de compostos isolados de Zingiber officinale por biotransformação e semi-síntese e avaliação frente à cisteinil-proteases
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Química - PPGQCâmpus São Carlos, 2016-07-01)
Several aromatic polyketide derivatives from Ginger (Zingiber officinale), like zingerone,
6-gingerol and 6-shogaol were obtained by biocatalytic reactions and semi-synthesis and
both their antifungal and cysteine-proteinase ...