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T regulatory cells-derived extracellular vesicles and their contribution to the generation of immune tolerance
(Wiley, 2020)
T regulatory (Treg) cells have a major role in the maintenance of immune tolerance against self and foreign antigens through the control of harmful inflammation. Treg cells exert immunosuppressive function by several ...
Metronomic chemotherapy in small animal practice: An update
(2016-01-01)
Metronomic chemotherapy can be considered a new chemotherapy modality involving continuous administration of low doses of cytostatic agents which targets endothelial cells. Endothelial cells are vital for the development ...
Trypanosoma cruzi Induces Regulatory B Cell Alterations in Patients With Chronic Chagas Disease
(Frontiers Media, 2021-08)
The clinical evolution of patients with chronic Chagas disease (CCD) is mainly associated with an excessive inflammation and a defective immunomodulatory profile caused by the interaction between T. cruzi and the host. ...