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Long-term high-fat diet-induced obesity decreases the cardiac leptin receptor without apparent lipotoxicity
(Pergamon-Elsevier B.V. Ltd, 2011-06-06)
Aims: Leptin resistance has been associated with cardiac lipotoxicity; however, whether leptin resistance is a risk factor associated with cardiac lipotoxicity at different time points in diet-induced obesity is unclear. ...
Perfil fisiológico de la leptina.
(2013-11-01)
Introducción: La leptina fue descubierta en el contexto de sus efectos sobre el control de la alimentación
y del gasto energético. Aunque en un principio se pensó que la leptina actuaba sólo sobre ciertos centros
hipotalámicos, ...
Administration of physiologic levels of triiodothyronine increases leptin expression in calorie-restricted obese rats, but does not influence weight loss
(W B Saunders Co-elsevier Inc, 2010-01-01)
Obesity has become a major public health problem, most commonly treated via dietary restriction to promote weight loss. Although leptin and thyroid hormones are involved in the regulation of energy balance, the role of ...
Administration of physiologic levels of triiodothyronine increases leptin expression in calorie-restricted obese rats, but does not influence weight loss
(W B Saunders Co-elsevier Inc, 2010-01-01)
Obesity has become a major public health problem, most commonly treated via dietary restriction to promote weight loss. Although leptin and thyroid hormones are involved in the regulation of energy balance, the role of ...
AdipoR1 mediates the anorexigenic and insulin/leptin-like actions of adiponectin in the hypothalamus
(Elsevier Science BvAmsterdamHolanda, 2008)
Reciprocal influences between leptin and glucocorticoids during acute Trypanosoma cruzi infection
(Springer, 2013-05)
Leptin and glucocorticoids (GCs) are involved in metabolic functions, thymic homeostasis and immune activity through complex interactions. We recently showed that C57BL/6 mice infected with Trypanosoma cruzi revealed a ...
Increased adipogenesis of osteoporotic human-mesenchymal stem cells (MSCs) is characterized by impaired leptin action
(WILEY-LISS, DIV JOHN WILEY & SONS INC, 2008-03-01)
The bone marrow contains mesenchymal stem cells (MSCs) that differentiate to the osteogenic and adipogenic lineages. The fact that the decrease in bone volume of age-related osteoporosis is accompanied by an increase in ...
Is “Leptin Resistance” Another Key Resistance to Manage Type 2 Diabetes?
(Bentham Science Publishers, 2020)
Although novel pharmacological options for the treatment of type 2 diabetes mellitus (DM2) have been observed to modulate the functionality of several key organs in glucose homeostasis, successful regulation of insulin ...
Long-term high-fat diet-induced obesity decreases the cardiac leptin receptor without apparent lipotoxicity
(Pergamon-Elsevier B.V. Ltd, 2014)