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Cyclic nucleotide specific phosphodiesterases of the kinetoplastida: A unified nomenclature
(Elsevier Science, 2006-01)
Presence of phosphodiesterase type 5 in the spinal cord and its involvement in bladder outflow obstruction related bladder overactivity
(Elsevier B.V., 2013-10-01)
Purpose: Phosphodiesterase type 5 inhibitors were recently introduced as a new treatment option for men with lower urinary tract symptoms. Safety and clinical effectiveness are well documented but the mode of action is ...
Evaluation of phthalazinone phosphodiesterase inhibitors with improved activity and selectivity against Trypanosoma cruzi
(Oxford University Press, 2020)
(E)-3,5-Dimethyl-1-p-tolyl-4-(p-tolyldiazenyl)-1H-pyrazole
(WILEY-BLACKWELL, 2012-02)
There are two independent molecules, A and B, in the asymmetric unit of the title compound, C19H20N4, in each of which the N=N double bond has an E conformation. The dihedral angles between the pyrazole ring and the p-tolyl ...
Role of cGMP and cAMP in the hemodynamic response to intrathecal sildenafil administration
(Faculdade de Medicina / USP, 2011)
INTRODUCTION: Results from our laboratory have demonstrated that intracerebroventricular administration of sildenafil to conscious rats promoted a noticeable increase in both lumbar sympathetic activity and heart rate, ...