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A functional study on gentamicin-related cochleotoxicity in its conventional dose in newborns
(ASSOC BRASILEIRA OTORRINOLARINGOLOGIA & CIRURGIA CERVICOFACIAL, 2010)
The early identification of hearing impairment allows for an intervention still in the ""critical"" and ideal period of hearing and language stimulation. Pediatric ototoxicity is a very controversial topic. There have been ...
A gain-of-function mutation in the α9 nicotinic acetylcholine receptor alters medial olivocochlear efferent short-term synaptic plasticity
(Society for Neuroscience, 2018-04)
Gain control of the auditory system operates at multiple levels. Cholinergic medial olivocochlear (MOC) fibers originate in the brainstem and make synaptic contacts at the base of the outer hair cells (OHCs), the final ...
Cellular and functional mechanisms involved in hearing loss in DFNA2 mouse model
(Sociedad Argentina de Investigación Bioquímica y Biología Molecular, 2021)
Function impairment in the voltage-gated K+ channel KCNQ4 is the main cause of DFNA2, a non-syndromic progressive hearing loss (HL). It occurs in two phases: initially, there is a mild HL at young ages, which then progresses ...
Activity of nAChRs containing α9 subunits modulates synapse stabilization via bidirectional signaling programs
(John Wiley & Sons Inc, 2009-12)
Although the synaptogenic program for cholinergic synapses of the neuromuscular junction is well known, little is known of the identity or dynamic expression patterns of proteins involved in non-neuromuscular nicotinic ...
Preventing presbycusis in mice with enhanced medial olivocochlear feedback
(National Academy of Sciences, 2020-05-26)
"Growing old" is the most common cause of hearing loss. Agerelated hearing loss (ARHL) (presbycusis) first affects the ability to understand speech in background noise, even when auditory thresholds in quiet are normal. ...
Enhanced hair cell postsynaptic responses alter release from presynaptic efferent neurons to prolong inhibition of the cochlea
(Association for Research in Otolaryngology, 2018)
Gain control of the auditory system operates at multiple levels. Cholinergic medial olivocochlear (MOC) fibers that originate in the brainstem and make direct synaptic contacts at the base of the outer hair cells (OHCs) ...
Tergal glands in termite soldiers of the subfamily Syntermitinae (Isoptera: Termitidae)
(Pergamon-Elsevier B.V. Ltd, 2012-02-01)
The subfamily Syntermitinae comprises 14 genera of termites that are exclusively neotropical. The present study reports morphological data about mandibulate nasute soldiers from termite species belonging to three different ...
Tergal glands in termite soldiers of the subfamily Syntermitinae (Isoptera: Termitidae)
(Pergamon-Elsevier B.V. Ltd, 2012-02-01)
The subfamily Syntermitinae comprises 14 genera of termites that are exclusively neotropical. The present study reports morphological data about mandibulate nasute soldiers from termite species belonging to three different ...
Stronger efferent suppression of cochlear neural potentials by contralateral acoustic stimulation in awake than in anesthetized chinchilla
(Frontiers Research Foundation, 2015)
© 2015 Aedo, Tapia, Pavez, Elgueda, Delano and Robles.There are two types of sensory cells in the mammalian cochlea, inner hair cells, which make synaptic contact with auditory-nerve afferent fibers, and outer hair cells ...
Effects of Electrical Stimulation of Olivocochlear Fibers in Cochlear Potentials in the Chinchilla
(SPRINGER, 2011-06)
The mammalian cochlea has two types of sensory cells; inner hair cells, which receive auditory-nerve afferent innervation, and outer hair cells, innervated by efferent axons of the medial olivocochlear (MOC) system. The ...