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Estudos dos mecanismos envolvidos na ação antinociceptiva causada pelo disseleneto de difenila em camundongos
(Universidade Federal de Santa MariaBRBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, 2007-08-01)
The interest in organoselenium biochemistry and pharmacology has increased in the last two decades due to a variety of organoselenium compounds that possess biological activity. Accordingly, diphenyl diselenide, a simple ...
Peripheral effect of a kappa opioid receptor antagonist on nociception evoked by formalin injected in TMJ of pregnant rats
(Pergamon-elsevier Science LtdOxfordInglaterra, 2005)
Clindamicina inibe a resposta nociceptiva em modelos de dores aguda e crônica por meio da ativação de mecanismos opioidérgicos e serotoninérgicos
(Universidade Federal de Minas GeraisUFMG, 2017-02-22)
Clindamycin is a lincosamide antibiotic used to treat patients with pneumonia, osteomielitis and skin infections. It has been recently demonstrated that clindamycin inhibits TNF-, IL-1 and prostaglandins production. Thus, ...
Teleantagonism: A pharmacodynamic property of the primary nociceptive neuron
(NATL ACAD SCIENCES, 2008)
Previous work from our group showed that intrathecal (i.t.) administration of substances such as glutamate, NMDA, or PGE(2) induced sensitization of the primary nociceptive neuron (PNN hypernociception) that was inhibited ...
Gonadal hormones decrease temporomandibular joint kappa-mediated antinociception through a down-regulation in the expression of kappa opioid receptors in the trigeminal ganglia
(Elsevier Science BvAmsterdamHolanda, 2009)
Avaliação da atividade antinociceptiva espinhal da toxina Tx3-4 do veneno da aranha Phoneutria nigriventer em camundongos
(Universidade Federal de Minas GeraisUFMG, 2009-10-21)
Existing medicines for the treatment of pain are often associated withserious side effects and rapid development of tolerance, thus, there is a need for new, more selective molecules. The inhibition of voltage-gated calcium ...
Nocicepção em prole adulta de camundongo em exposição à morfina no período gestacional e lactaçãoNociception off spring in mouse adult exposed to morphine during pregnancy and lactation
(Universidade Federal do ParáBrasilInstituto de Ciências da SaúdeUFPAPrograma de Pós-Graduação em Ciências Farmacêuticas, 2017)
Avaliação da atividade antinociceptiva espinal da toxina Ph1 isolada dp veneno da Phoneutria nigriventer em rodedores
(Universidade Federal de Minas GeraisUFMG, 2008-12-03)
Calcium influx through voltage sensitive calcium channels (VSCCs) plays an important role on the nociceptive transmission in the dorsal horn of the spinal cord. The intrathecal administration of VSCCs blockers, such as ...