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Development of a caffeic acid-phthalimide hybrid compound for NADPH oxidase inhibition
(2021-05-12)
NADPH oxidases are pharmacological targets for the treatment of inflammation-based diseases. This work presents the synthesis and study of a caffeic acid/phthalimide hybrid compound (C2) as a potential inhibitor of NADPH ...
Contribution of NADPH oxidase and the endoplasmic reticulum calcium release in the establishment of hippocampal neuronal polarity and axonal growth
(2015)
Reactive Oxygen Species (ROS) from NADPH (NOX) contribute to LTP, memory
consolidation and neuronal actin cytoskeleton dynamics. Physiological levels of ROS also
promote Ca2+ release from the endoplasmic reticulum (ER). ...
The reactivity of oytho-methoxy-substituted catechol radicals with sulfhydryl groups: Contribution for the comprehension of the mechanism of inhibition of NADPH oxidase by apocynin
(Elsevier B.V., 2007-08-01)
Redox processes are involved in the mechanism of action of NADPH oxidase inhibitors such as diphenyleneiodonium and apocynin. Here, we studied the structure-activity relationship for apocynin and analogous ortho-methoxy- ...
The reactivity of oytho-methoxy-substituted catechol radicals with sulfhydryl groups: Contribution for the comprehension of the mechanism of inhibition of NADPH oxidase by apocynin
(Elsevier B.V., 2007-08-01)
Redox processes are involved in the mechanism of action of NADPH oxidase inhibitors such as diphenyleneiodonium and apocynin. Here, we studied the structure-activity relationship for apocynin and analogous ortho-methoxy- ...
Increased aortic NADPH oxidase activity in rats with genetically high angiotensin-converting enzyme levels
(LIPPINCOTT WILLIAMS & WILKINS, 2005)
In humans and rats, angiotensin I-converting enzyme activity is significantly determined by a gene polymorphism. Homozygous Brown Norway rats have higher plasma angiotensin I-converting enzyme activity and circulating ...
Moderate exercise training decreases aortic superoxide production in myocardial infarcted rats
(SPRINGER, 2008)
Myocardial infarction (MI) has been associated with increases in reactive oxygen species (ROS). Exercise training (ET) has been shown to exert positive modulations on vascular function and the purpose of the present study ...
Inibição sistêmica da NADPH oxidase: estudo do coração de ratos espontaneamente hipertensos com diabetes mellitus
(Universidade Estadual Paulista (UNESP), 2016)
Inibição sistêmica da NADPH oxidase: estudo do coração de ratos espontaneamente hipertensos com diabetes mellitus
(Universidade Estadual Paulista (Unesp), 2016)
Lipopolysaccharide treatment reduces rat platelet aggregation independent of intracellular reactive-oxygen species generation
(Informa HealthcareLondon, 2012)
Which comes first: Renal inflammation or oxidative stress in spontaneously hypertensive rats?
(Taylor & Francis LtdAbingdonInglaterra, 2007)