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Expression of peroxiredoxins I and IV in multiple myeloma: association with immunoglobulin accumulation
(SpringerNew YorkEUA, 2013)
ISS WAS HIGHLY PREDICTIVE OF PROGNOSIS IN A BRAZILIAN STUDY IN MYELOMA PATIENTS
(Ferrata Storti Foundation, 2008-06-01)
Percutaneous vertebroplasty for multiple myeloma of the cervical spine
(SPRINGER, 2009)
Spinal involvement is a common presentation of multiple myeloma (MM); however, the cervical spine is the least common site of myelomatous involvement. Few studies evaluate the results of percutaneous vertebroplasty (PV) ...
Number of expressed cancer/testis antigens identifies focal adhesion pathway genes as possible targets for multiple myeloma therapy
(TAYLOR & FRANCIS LTD, 2010)
Considering that the importance of cancer/testis (CT) antigens in multiple myeloma (MM) biology is still under investigation, the present study aimed to: (1) identify genes differentially expressed in MM using microarray ...
TGF beta R2 aberrant methylation is a potential prognostic marker and therapeutic target in multiple myeloma
(Wiley-Blackwell, 2009-10-15)
Multiple myeloma (MM) is an incurable hematological malignancy. Different studies demonstrated the occurrence of genetic and epigenetic alterations in MM. the aberrant methylation is one of the most frequent epigenetic ...
Proteasome and heat shock protein 70 (HSP70) inhibitors as therapeutic alternative in multiple myeloma
(Impact Journals Llc, 2017)
HSP70 connects multiple signaling pathways that work synergistically to protect tumor cells from death by proteotoxic stress and represents a possible target to establish a new approach for multiple myeloma treatment. ...
Is there any relationship between gene expression of tumor antigens and CD4(+) T cells in multiple myeloma?
(Future Medicine Ltd, 2014-05-01)
Aim: the present study aimed at correlating the expression of cancer/testis antigens (CTAs) with the expression of genes related to tumor-infiltrating T cells. Materials & methods: MAGE-C1/CT-7, MAGEA3/6, NY-ESO-1, LAGE-1 ...
Peroxiredoxin I is differentially expressed in multiple myelomas and in plasmablastic lymphomas
(WILEY-BLACKWELL, 2008)
BACKGROUND: Plasmablastic lymphoma (PBL) and multiple myeloma (MM) are B cell-derived malignancies that share many morphologic and immunophenotypic traits, making the differential diagnosis particularly complicated. We ...
Number of expressed cancer/testis antigens identifies focal adhesion pathway genes as possible targets for multiple myeloma therapy
(Taylor & Francis Ltd, 2010-08-01)
Considering that the importance of cancer/testis (CT) antigens in multiple myeloma (MM) biology is still under investigation, the present study aimed to: (1) identify genes differentially expressed in MM using microarray ...
Analysis of polymorphism at site -174 G/C of interleukin-6 promoter region in multiple myeloma
(Associação Brasileira de Divulgação Científica, 2007-02-01)
It is well established that interleukin-6 (IL-6) is an essential growth factor for multiple myeloma (MM) and patients with increased IL-6 levels have a poor prognosis. In healthy subjects, the presence of the C allele at ...