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Participação do receptor toll-like4 na resposta imune durante a esporotricose ecperimental
(Universidade Estadual Paulista (Unesp), 2008-11-18)
Os receptores “toll-like” (TLR) são importantes no reconhecimento de patógenos por um hospedeiro e conseqüentemente para a ativação da resposta imune inata. Evidências clínicas e experimentais mostram que defeitos nesses ...
Ifn-g induction by the tc13tul antigen from trypanosoma cruzi in naïve balb/c mice
(Medicina (Buenos Aires), 2019)
Trypanosoma cruzi, the etiological agent of Chagas disease, releases factors which modulate the host immune responses, including Tc13 antigens. Regarding innate immune responses, Tc13 antigen from Tulahuén strain, Tc13Tul, ...
Murine myeloid progenitor responses to GM-CSF and eosinophil precursor responses to IL-5 represent distinct targets for downmodulation by prostaglandin E2
(British Pharmacological Society, 2013)
Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism
(FEDERATION AMER SOC EXP BIOLBETHESDA, 2012)
Nonalcoholic fatty liver disease (NAFLD) is a major health problem and a leading cause of chronic liver disease in the United States and developed countries. In humans, genetic factors greatly influence individual ...
Fibrosis-associated hepatocarcinogenesis revisited: Establishing standard medium-term chemically-induced male and female models
(2018-09-01)
Hepatocellular carcinoma causes ~10% of all cancer-related deaths worldwide, usually emerging in a background of liver fibrosis/cirrhosis (70%-90% of cases). Chemically-induced mouse models for fibrosis-associated ...
Impairment Of Toll-like Receptors 2 And 4 Leads To Compensatory Mechanisms After Sciatic Nerve Axotomy
(Biomed Central LtdLondon, 2016)