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Induction of HIF-1α by HIV-1 infection in CD4 + T cells promotes viral replication and drives extracellular vesicle-mediated inflammation
(American Society for Microbiology, 2018-09)
Chronic immune activation and inflammation are hallmarks of HIV-1 infection and a major cause of serious non-AIDS events in HIV-1-infected individuals on antiretroviral treatment (ART). Herein, we show that cytosolic ...
Thymopentin improves the survival of septic mice by promoting the production of 15-deoxy-prostaglandin J2 and activating the PPARγ signaling pathway
(Federation of American Societies for Experimental Biology, 2020-09)
Sepsis, a systemic inflammatory response syndrome (SIRS) caused by infection, is a major public health concern with limited therapeutic options. Infection disturbs the homeostasis of host, resulting in excessive inflammation ...
Evaluation of immune response, microbiota, and blood markers after probiotic bacteria administration in obese mice induced by a high-fat diet
(Elsevier Science Inc, 2014-11)
Objective: Obesity is associated with alterations in intestinal microbiota and immunity. The aim of this study was to determine the effect of probiotic Lactobacillus casei CRL 431 administration on intestinal and humoral ...
Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases
(American Society for Clinical Investigation, 2020-04)
BACKGROUND. Undifferentiated systemic autoinflammatory diseases (USAIDs) present diagnostic and therapeutic challenges. Chronic interferon (IFN) signaling and cytokine dysregulation may identify diseases with available ...
The role of efferocytosis in autoimmune diseases
(Frontiers Media S.A., 2018)
The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal-fetal homeostasis
(NLM (Medline), 2022)
In brief: The syndrome of preterm labor comprises multiple established and novel etiologies. This review summarizes the distinct immune mechanisms implicated in preterm labor and birth and highlights potential strategies ...
Estudo do papel modulador de adipócitos na ativação macrofágica durante a infecção por Mycobacterium bovis BCG in vitro
(Universidade Federal de Juiz de Fora (UFJF)BrasilICB – Instituto de Ciências BiológicasPrograma de Pós-graduação em Ciências Biológicas: Imunologia e Doenças Infecto-Parasitárias/Genética e BiotecnologiaUFJF, 2018)