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Bradicinina 1-5 activa el receptor B1 de cininas e induce la fosforilación de mapk en células epidérmicas humanas en cultivo
(Universidad Austral de Chile - Sistema de Bibliotecas - Programa Cybertesis, 2003)
The ERK1/2 pathway regulates testosterone synthesis by coordinately regulating the expression of steroidogenic enzymes in Leydig cells
(Elsevier Ireland, 2013-03-07)
Adult mice with a Leydig cell specific deletion of MAPK kinase (MEK) 1 and 2 (Mek1(f)(/)(f);Mek2(-/-);Cre(+)) mice display Leydig cell hypoplasia and hypergonadotropic hypogonadism. We used radioimmunoassays and quantitative ...
Differential involvement of ERK1-2 and p38MAPK activation on Swiss 3T3 cell proliferation induced by prostaglandin F2alpha
(Elsevier Science, 2006-12)
Prostaglandin F2alpha (PGF2alpha) induces cyclin D1 expression and DNA synthesis in Swiss 3T3 cells. In order to assess which signaling mechanisms are implicated in these processes, we have used both a pharmacological ...
Análisis de la Vía de señalización de las Integrinas-MAPK en cáncer de ovario
(07/03/2012)
ABSTRACT: Ovarian carcinoma (CaO) is one of the most aggressive gynecological malignancies, over 50% of patients affected by this disease die, this is mainly due to the fact that the disease is asymptomatic in the early ...
Mitogen-activated protein kinase is increased in the limbic structures of the rat brain during the early stages of status epilepticus
(Elsevier B.V., 1998-10-01)
Systemic administration of pilocarpine (PILO) in adult rat produces acute limbic seizures leading to states epilepticus. Recent studies have shown the activation of mitogen-activated protein kinase (MAPK) cascades during ...
How mitogen-activated protein kinases recognize and phosphorylate their targets: A QM/MM study
(American Chemical Society, 2009-05)
Mitogen-activated protein kinase (MAPK) signaling pathways play an essential role in the transduction of environmental stimuli to the nucleus, thereby regulating a variety of cellular processes, including cell proliferation, ...
Ovarian steroid receptors and activated MAPK in the regional decidualization in rats
(Society For The Study Of Reproduction, 2011-05)
Though the decidua serves a critical function in implantation, the hormonal regulated pathway in decidualization is still elusive. Here we describe in detail the regional distribution and the effects of progesterone receptors ...
High glucose concentration stimulates NHE-1 activity in distal nephron cells: the role of the Mek/Erk1/2/p90RSK and p38MAPK signaling pathways
(Basel, 2014)
AIMS:
In models of diabetes, distal nephron cells contribute to glucose uptake and oxidation. How these cells contribute to the use of glucose for the regulation of H(+) extrusion remains unknown. We used Madin-Darby ...
An Asp49 Phospholipase A(2) from Snake Venom Induces Cyclooxygenase-2 Expression and Prostaglandin E-2 Production via Activation of NF-kappa B, p38MAPK, and PKC in Macrophages
(Hindawi Publishing CorporationNew YorkEUA, 2014)