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Modulation of the Shaker K+ channel gating kinetics by the S3-S4 linker
(ROCKEFELLER UNIV PRESS, 2000-02)
In Shaker K+ channels depolarization displaces outwardly the positively charged residues of the S4 segment. The amount of this displacement is unknown, but large movements of the S4 segment should be con strained by the ...
Gating, regulation, and structure in k2p k+ channels: in varietate concordia?
(2016)
K-2P K+ channels with two pore domains in tandem associate as dimers to produce so-called background conductances that are regulated by a variety of stimuli. Whereas gating in K-2P channels has been poorly understood, ...
ROLE OF CA2+-DEPENDENT K-CHANNELS IN THE MEMBRANE-POTENTIAL AND CONTRACTILITY OF AORTA FROM SPONTANEOUSLY HYPERTENSIVE RATS
(Stockton Press, 1994-11-01)
1 Contractile responses to KCl and membrane potentials were determined in aortic rings from spontaneously hypertensive rats (SHR), normotensive Wistar rats (NWR) and Wistar Kyoto rats (WKY) both in the absence and in the ...
Orientation of Arabidopsis thaliana KAT1 channel in the plasma membrane
(2004)
The Arabidopsis thaliana KAT1, an inward-rectifying potassium channel, shares molecular features with the Shaker family of outward rectifier K(+) channels. The KAT1 amino-acid sequence reveals the presence of a positively ...
Functional transplantation of chloride channels from the human syncytiotrophoblast microvillous membrane to Xenopus oocytes
(2002)
The materno-fetal transfer of metabolites and nutrients requires the operation of specific transport mechanisms through syncytiotrophoblast membranes. Electrophysiological studies on these cells are scarce and, because of ...
K+ Conduction and Mg2+ Blockade in a Shaker Kv-Channel Single Point Mutant with an Unusually High Conductance
(CELL PRESS, 600 TECHNOLOGY SQUARE, 5TH FLOOR, CAMBRIDGE, MA 02139 USA, 2012)
The molecular basis for an allosteric inhibition of k+-flux gating in k2p channels
(eLife Sciences Publications Ltd, 2019)
An Extracellular Ion Pathway Plays a Central Role in the Cooperative Gating of a K-2P K+ Channel by Extracellular pH
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3996 USA, 2013)
Electrophysiological characterization of potassium conductive pathways in Trypanosoma cruzi
(2011)
Potassium channels (K+ channels) are members of one of the largest and most diverse families of membrane proteins, widely described from bacteria to humans. Their functions include voltage-membrane potential maintenance, ...