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Mostrando ítems 41-50 de 183
Desenvolvimento de nanoformulações de uso tópico contendo Anfotericina B e Clorito de sódio para Leishmaniose Tegumentar
(Instituto Gonçalo Moniz, 2018)
American Cutaneous Leishmaniasis (ACL) is a polymorphic disease of the skin and mucosa caused by the parasite of the genus Leishmania. Treatment options have limitations, especially toxicity and drug esistance,compromising ...
Targeting calcium homeostasis as the therapy of Chagas’ disease and leishmaniasis – a review
(Tropical Biomedicine, 2013)
Phenotypic diversity and drug susceptibility of Trypanosoma cruzi TcV clinical isolates
(PLoS, 2018)
Trypanosoma cruzi is a genetically heterogeneous group of organisms that cause Chagas disease. It has been long suspected that the clinical outcome of the disease and response to therapeutic agents are, at least in part, ...
Phenotypic diversity and drug susceptibility of Trypanosoma cruzi TcV clinical isolates
(Public Library of Science, 2018-09)
Trypanosoma cruzi is a genetically heterogeneous group of organisms that cause Chagas disease. It has been long suspected that the clinical outcome of the disease and response to therapeutic agents are, at least in part, ...
Effects of artesunate against Trypanosma cruzi
(Academic Press Inc Elsevier Science, 2015-09)
Therapy against Trypanosma cruzi relies on only two chemically relatednitro-derivative drugs, benznidazole and nifurtimox, both limited by poorefficacy and toxicity. It is suspected that with prolonged usage of these drugs, ...
Evaluation of antileishmanial activity of harzialactone a isolated from the marine-derived fungus Paecilomyces sp
(2019-01-01)
Fractionation of extracts from the culture broth of the marine-derived fungus, Paecilomyces sp. 7A22, resulted in the isolation of the harzialactone A (HA), a known compound previously isolated from fungi of marine ...
In Vitro Assessment of Plants Growing in Cuba Belonging to Solanaceae Family Against Leishmania amazonensis
(Wiley-Blackwell, 2016-11-01)
In this study, an in vitro antileishmanial assessment of plant extracts from 12 genera and 46 species growing in Cuba belonging to Solanaceae family was performed. A total of 226 extracts were screened against promastigotes ...