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IRF8 Mutations and Human Dendritic-Cell Immunodeficiency
(MASSACHUSETTS MEDICAL SOC, 2011)
BACKGROUND
CCL20 and Beta-defensin 2 Production by Human Lung Epithelial Cells and Macrophages in Response to Brucella abortus infection
(Public Library Of Science, 2015-10)
Both CCL20 and human β-defensin 2 (hBD2) interact with the same membrane receptor and display chemotactic and antimicrobial activities. They are produced by airway epithelia in response to infectious agents and proinflammatory ...
Innate immune response during DENV-2 infection of monocytes/macrophages
(InmunovirologíaMedellín - Colombia, 2022)
TLR Crosstalk Activates LRP1 to Recruit Rab8a and PI3K gamma for Suppression of Inflammatory Responses
(2018)
The multi-ligand endocytic receptor, low-density lipoprotein-receptor-related protein 1 (LRP1), has anti-inflammatory roles in disease. Here, we reveal that pathogen-activated Toll-like receptors (TLRs) activate LRP1 in ...
Characterization of small extracellular vesicles released by human primary macrophages and their ability to propagate resistance to HIV-1 replication
(2021)
Vesículas extracelulares (VEs) são liberadas por virtualmente todos os tipos de células, e participam da comunicação intercelular por meio do transporte e transferência de moléculas bioativas, como ácidos nucléicos, ...
Suppression of plasma hepcidin by venesection during steady-state hypoxia
(Elsevier, 2016)
Hepcidin inhibits iron uptake from the gut and release of iron from macrophages in the reticuloendothelial system. Suppression of plasma hepcidin occurs in lowlanders after ascent to high altitude, reflecting the increased ...