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Heparan sulfate potentiates leukocyte adhesion on cardiac fibroblast by enhancing Vcam-1 and Icam-1 expression
(Elsevier, 2018)
Cardiac fibroblasts (CF) act as sentinel cells responding to chemokines, cytokines and growth factors released in cardiac tissue in cardiac injury events, such as myocardial infarction (MI). Cardiac injury involves the ...
Cathepsin X binds to cell surface heparan sulfate proteoglycans
(Elsevier B.V., 2005-04-15)
Glycosaminoglycans have been shown to be important regulators of activity of several papain-like cathepsins. Binding of glycosaminoglycans to cathepsins thus directly affects catalytic activity, stability or the rate of ...
El Heparán Sulfato y la descondensación del núcleo espermático humano: estudio de su rol específico en dicho proceso y caracterización molecular de la interacción Heparán Sulfato-ADN-ProtaminasHeparan sulfate and nuclear sperm decondensation in humans: study of its specific role in this process and molecular characterization of heparan sulfate-DNA-Protamines interaction
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2012)
Effect of different glycosaminoglycans in a guinea-pig carotid-artery thrombosis model
(Elsevier B.V., 2014)
The modulatory role of sulfated and non-sulfated small molecule heparan sulfate-glycomimetics in endothelial dysfunction: absolute structural clarification, molecular docking and simulated dynamics, SAR analyses and ADMET studies
(Royal Soc Chemistry, 2021-04-23)
The conceptual technology of small molecule glycomimetics, exemplified by compounds C1-4, has shown promising protective effects against lipid-induced endothelial dysfunction, restorative effects on diabetic endothelial ...
A comparative-analysis of glycosaminoglycans from human umbilical arteries in normal subjects and in pathological conditions affecting pregnancy
(Williams & Wilkins, 1992-11-01)
BACKGROUND: Vascular cells express different phenotypes in adult and fetal vessels, and the extracellular matrix they synthesize should reflect these differences. Alterations of vascular proteoglycan/glycosaminoglycan is ...