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Andrographolide interferes with binding of nuclear factor-kb to dna in hl-60-derived neutrophilic cells
(WILEY-BLACKWELL, 2005)
1 Andrographolide, the major active component from Andrographis paniculata, has shown to possess anti-inflammatory activity. Andrographolide inhibits the expression of several proinflammatory proteins that exhibit a nuclear ...
Saponins from the rhizomes of Chamaecostus subsessilis and their cytotoxic activity against HL60 human promyelocytic leukemia cells
(Academic Association of Pharmaceutical Sciences from Antofagasta, 2020)
Xylodiol from Xylopia langsdorfiana induces apoptosis in HL60 cells
(Soc Brasileira FarmacognosiaJoao PessoaBrasil, 2011)
Antitumor potential of the myotoxin BthTX-I from Bothrops jararacussu snake venom: evaluation of cell cycle alterations and death mechanisms induced in tumor cell lines
(BioMed Central, 2015)
Abstract
Background
Phospholipases A2 (PLA2s) are abundant components of snake venoms that have been extensively studied due to their pharmacological and pathophysiological ...
Antiproliferative activity of pristimerin isolated from Maytenus ilicifolia (Celastraceae) in human HL-60 cells
(Pergamon-Elsevier B.V. Ltd, 2014)
Synthesis and preliminary evaluation of 3-thiocyanato-1H-indoles as potential anticancer agents
(Elsevier France-editions Scientifiques Medicales Elsevier, 2016-08)
A novel series of twenty 3-thiocyanato-1H-indoles, carrying diversification at positions N-1, C-2 and C-5 of the heterocyclic core, were synthesized; their antiproliferative activity against four human cancer cell lines ...
Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor
(Elsevier, 2016)
Herein we report the design, synthesis, bioinformatic and biological studies of benzimidazole and benzothiophene derivatives as new cannabinoid receptor ligands. To test the hypothesis that the lack of a hydrogen bond ...