Buscar
Mostrando ítems 41-50 de 298
Secreted protein acidic and rich in cysteine (SPARC) induces epithelial-mesenchymal transition, enhancing migration and invasion, and is associated with high Gleason score in prostate cancer
(2019)
Secreted protein acidic and rich in cysteine (SPARC) is a matricellular protein highly expressed in bone tissue that acts as a chemoattractant factor promoting the arrival of prostate cancer (PCa) cells to the bone marrow. ...
The expression of syndecan-1 and -2 is associated with Gleason score and epithelial-mesenchymal transition markers, E-cadherin and β-catenin, in prostate cancer
(2010)
The epithelial-mesenchymal transition (EMT) is considered a key step in tumor progression, where the invasive cancer cells change from epithelial to mesenchymal phenotype. During this process, a decrease or loss in adhesion ...
The accuracy of pathological data for the prediction of insignificant prostate cancer
(BRAZILIAN SOC UROLRIO DE JANEIRO, 2012-11)
Introduction: The widespread screening programs prompted a decrease in prostate cancer stage at diagnosis, and active surveillance is an option for patients who may harbor clinically insignificant prostate cancer (IPC). ...
p-mTOR, p-4EBP-1 and eIF4E expression in canine prostatic carcinoma
(2019-02-01)
The mTOR/4E-BP1/eIF4E pathway plays important roles in the neoplastic transformation process and in tumour growth. In men, the mTOR/4E-BP1/eIF4E pathway was described as altered in different tumours, including prostate ...
Comparison of positivity frequency of bcl-2 expression in prostate adenocarcinoma with low and high Gleason score
(Associação Paulista de Medicina - APM, 2001-07-01)
CONTEXT: Multiple genetic and epigenetic factors have been implicated in the oncogenesis and progression of prostate cancer. The major difficulty is in that the clinical management stems from the reality that reliable and ...
Correlação anatomopatológica entre a amostragem por agulha ea amostragem cirúrgica no câncer de próstata: variabilidade interobservador
(Universidade Federal de Minas GeraisUFMG, 2007-02-15)
Prostatic adenocarcinoma has variable clinical evolution and the Gleason grading is its main prognostic factor. Diagnosis and classification are done through anatomic pathological testing which, although used to diagnose ...
Serum PSA and cure perspective for prostate cancer in males with nonpalpable tumor
(Sociedade Brasileira de Urologia, 2005-10-01)
INTRODUCTION: Many studies have shown the association between PSA levels and the subsequent detection of prostate cancer. In the present trial, we have studied the relationship between preoperative PSA levels and clinical ...