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Muc1, glycans and the cell-surface barrier to embryo implantation
(PORTLAND PRESS, 2001)
Muc1 and glycan expression in the oviduct and endometrium of the new world monkey cebus apella
(SOCIETY FOR THE STUDY OF REPRODUCTION, 2001)
Expression of bladder cancer‑associated glycans in murine tumor cell lines
(Spandidos Publications, 2019-03)
The characterization of murine cell lines is of great importance in order to identify preclinical models that could resemble human diseases. Aberrant glycosylation includes the loss, excessive or novel expression of glycans ...
Neurological disorders-associated anti-glycosphingolipid IgG-antibodies display differentially restricted IgG subclass distribution
(Nature, 2020-12)
Antibodies against several self-glycans on glycosphingolipids are frequently detected in different neurological disorders. Their pathogenic role is profusely documented, but the keys for their origin remain elusive. ...
Turning 'sweet' on immunity: galectin–glycan interactions in immune tolerance and inflammation
(Macmillan Publisher Limited, 2009-05)
The function of deciphering the biological information encoded by the glycome, which is the entire repertoire of complex sugar structures expressed by cells and tissues, is assigned in part to endogenous glycan-binding ...
Untangling galectin-driven regulatory circuits in autoimmune inflammation
(Elsevier, 2018-04)
Although significant progress has been made in understanding the mechanisms implicated in the pathogenesis and resolution of autoimmune inflammation, studies aimed at identifying mediators of these pathways are necessary ...
Cracking the “Sugar Code”: A Snapshot of N- and O-Glycosylation Pathways and Functions in Plants Cells
(Frontiers Media, 2021-02)
Glycosylation is a fundamental co-translational and/or post-translational modification process where an attachment of sugars onto either proteins or lipids can alter their biological function, subcellular location and ...
Extrinsic functions of lectin domains in O-N-acetylgalactosamine glycan biosynthesis
(American Society for Biochemistry and Molecular Biology, 2016-12)
Glycan biosynthesis occurs mainly in Golgi. Molecular organization and functional regulation of this process are not well understood. We evaluated the extrinsic effect of lectin domains (β-trefoil fold) of polypeptide ...
Regulatory role of glycans in the control of hypoxia-driven angiogenesis and sensitivity to anti-angiogenic treatment
(Oxford University Press, 2014-08-12)
Abnormal glycosylation is a typical hallmark of the transition from healthy to neoplastic tissues. Although the importance of glycans and glycan-binding proteins in cancer-related processes such as tumor cell adhesion, ...
Factors affecting the computation of the 13C shielding in disaccharides
(Wiley, 2014-09)
Knowledge of the three-dimensional structures of glycans and glycoproteins is useful for a full understanding of molecular processes in which glycans are involved, such as antigen-recognition and virus infection, to name ...