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Polymorphic stability of darunavir and its formulation
(2016-03-01)
Darunavir (DAR) is a synthetic antiretroviral drug widely used around the world as an important component of HIV therapy. Usually, DAR is commercialized at ethanolate crystalline form. Under different environmental conditions, ...
Effect of cooking on the stability of veterinary drug residues in chicken eggs
(Taylor & Francis Ltd, 2019-05)
The available information on drug residue stability in chicken egg is scarce. The objective of this study was to evaluate the stability of drug residues in egg under different traditional cooking procedures. Fresh eggs ...
Assessment of the physicochemical properties and stability for pharmaco-kinetic prediction of pyrazinoic acid derivatives
(2020-01-01)
Background: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis, which still has high prevalence worldwide. In addition, cases of drug resistance are frequently observed. In the search for new ...
UHPLC Quantitation Method and In vitro Studies of Two New Phthalimide Derivatives Planned to Treat Sickle Cell Disease
(Bentham Science Publ Ltd, 2017-01-01)
Background: Sickle cell disease is characterized by the occurrence of acute disability and progressive organ damage, and it is one of the most common and severe monogenic disorders around the world. Since hydroxycarbamide ...
Insights into Protein-Ionic Liquid Interactions Aiming at Macromolecule Delivery Systems
(Soc Brasileira Quimica, 2018-10-01)
Over the last few years, researchers have started to explore a particular class of compounds defined as ionic liquids (ILs) in attempts to use their unique characteristics. Since ILs have a very low vapor pressure, these ...
Preparação e caracterização inicial de complexo de inclusão entre nitrofurazona e 2-hidroxipropil-β-ciclodextrina
(2007-12-01)
Nitrofurazone (NF), 5-nitro-2-furaldehyde semicarbazone, a broad-spectrum antibiotic, has reported toxic effects and low solubility in water. It would be of great interest to form inclusion complexes between NF and a ...
Preparação e caracterização inicial de complexo de inclusão entre nitrofurazona e 2-hidroxipropil-β-ciclodextrina
(2007-12-01)
Nitrofurazone (NF), 5-nitro-2-furaldehyde semicarbazone, a broad-spectrum antibiotic, has reported toxic effects and low solubility in water. It would be of great interest to form inclusion complexes between NF and a ...