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Central, but not basolateral, amygdala involvement in the anxiolytic-like effects of midazolam in rats in the elevated plus maze
(SAGE PUBLICATIONS LTDLONDON, 2012)
The role of the amygdala in the mediation of fear and anxiety has been extensively investigated. However, how the amygdala functions during the organization of the anxiety-like behaviors generated in the elevated plus maze ...
Impaired brain glucose metabolism and presynaptic dopaminergic functioning in a mouse model of schizophrenia
(Springer, 2020-04)
Background: Schizophrenia is a disease diagnosed by visible signs and symptoms from late adolescence to early adulthood. The etiology of this disease remains unknown. An objective diagnostic approach is required. Here, we ...
Distinctive modulation of dopamine release in the nucleus accumbens shell mediated by dopamine and acetylcholine receptors
(Society for Neuroscience, 2017-11-15)
Nucleus accumbens (NAc) shell shows unique dopamine (DA) signals in vivo and plays a unique role in DA-dependent behaviors such as reward-motivated learning and the response to drugs of abuse.Adisynaptic mechanism forDArelease ...
Estudo da remodelação dos mapas motores corticais após o acidente vascular encefálico isquêmico: efeito da reabilitação combinada baseada no enriquecimento ambiental e (re)aprendizagem motora
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM NEUROCIÊNCIAS, 2019-02-22)
Over the past decades, Brazilian population over 60 years of age has increased, as
well as chronic diseases related to aging. Among these, stroke, one of the main causes
of hospitalizations and mortality in Brazil; causing ...
The role of nicotinic cholinergic neurotransmission in delusional thinking
(Nature Publishing Group, 2020-12)
Delusions are a difficult-to-treat and intellectually fascinating aspect of many psychiatric illnesses. Although scientific progress on this complex topic has been challenging, some recent advances focus on dysfunction in ...
Fronto-Subcortical Circuits for Cognition and Motivation: Dissociated Recovery in a Case of Loss of Psychic Self-Activation
(Frontiers Ed., 2019-01)
In humans and non-humans primates, extensive evidence supports the existence of subcortico-cortical circuits for cognition and behavior. Lesions studies are critical to understand the clinical significance of these ...
The role of nicotinic cholinergic neurotransmission in delusional thinking
(Nature Research, 2020)
Abstract: Delusions are a difficult-to-treat and intellectually fascinating aspect of many psychiatric illnesses. Although scientific progress on
this complex topic has been challenging, some recent advances focus on ...
A nitric oxide synthase inhibitor decreases 6-hydroxydopamine effects on tyrosine hydroxylase and neuronal nitric oxide synthase in the rat nigrostriatal pathway
(ELSEVIER SCIENCE BV, 2008)
There is evidence that nitric oxide plays a role in the neurotransmitter balance within the basal ganglia and in the pathology of Parkinson`s disease. In the present work we investigated in striatal 6-hydroxydopamine ...
Spontaneously Hypertensive Rats (SHR) Are Resistant to a Reserpine-Induced Progressive Model of Parkinson's Disease: Differences in Motor Behavior, Tyrosine Hydroxylase and alpha-Synuclein Expression
(Frontiers Media Sa, 2017)
Reserpine is an irreversible inhibitor of vesicular monoamine transporter-2 (VMAT2) used to study Parkinson's disease (PD) and screening for antiparkinsonian treatments in rodents. Recently, the repeated treatment with a ...