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EFFECTS of ENDOTHELIN-1 ON the ISOLATED GUINEA-PIG ILEUM - ROLE of NA+ IONS
(Springer, 1990-12-01)
Endothelin-1 induced an unusual transient biphasic effect (relaxation followed by contraction) in the isolated guinea-pig ileum. the contractile component of the response was concentration-dependent in the dose range ...
EFFECTS of ENDOTHELIN-3 ON the ISOLATED GUINEA-PIG ILEUM - ROLE of NA+ IONS and ENDOTHELIN RECEPTOR SUBTYPES
(Elsevier B.V., 1992-04-22)
Endothelin-3 induced a relaxation followed by contraction in the isolated guinea-pig ileum. the contractile but not the relaxant component of the response was concentration-dependent in the dose range studied. Neuronal ...
Tyrosine phosphorylation differentially fine-tunes ionotropic and metabotropic responses of human α7 nicotinic acetylcholine receptor
(Springer Nature Switzerland, 2021-05-24)
The α7 nicotinic acetylcholine receptor is involved in neurological, neurodegenerative, and inflammatory disorders. It operates both as a ligand-gated cationic channel and as a metabotropic receptor in neuronal and ...
Reduction of G protein-coupled receptor kinase 2 expression in U-937 cells attenuates H2 histamine receptor desensitization and induces cell maturation
(American Society for Pharmacology and Experimental Therapeutics, 2002-12)
Histamine and H2 agonists transiently induce an important cAMP response in promonocytic U-937 cells but fail to induce monocytic differentiation because of a rapid receptor desensitization mediated by G protein-coupled ...
Efficacy of a bioactive material and nanostructured desensitizing on dentin hypersensitivity treatment
(Universidade Estadual Paulista Júlio de Mesquita Filho, 2016-06-01)
AbstractIntroduction Dentin hypersensitivity is a frequent occurrence in dental practice. It is clinically characterized by acute, short, and temporary pain in response to mechanical, chemical, thermal, or osmotic stimuli ...
Treatment of PTSD by eye movement desensitization reprocessing (EMDR) improves sleep quality, quality of life, and perception of stress
(Blackwell Publishing, 2006-01-01)
The impact of posttraumatic stress disorder (PTSD) on the sleep of patients is widely reported. However, the parameters that can be altered are not the same for all patients. Some studies report an impairment of sleep ...
Hydrogen peroxide removes TRPM4 current desensitization conferring increased vulnerability to necrotic cell death
(2010)
Necrosis is associated with an increase in plasma membrane permeability, cell swelling, and loss of membrane integrity with subsequent release of cytoplasmic constituents. Severe redox imbalance by overproduction of reactive ...
Metabolic changes of arachidonic acid in aspirin desensitization [Cambios metabolicos del acido araquidonico en la desensibilizacion a la aspirina]
(1996)
Aspirin sensitivity occurs in 10% of all asthmatic patients. In this subset of asthmatics, nasal congestion and bronchospasm occurs between 30-180 minutes after ingestion of aspirin. Following a respiratory reaction to ...
The influence of a dentin desensitizer on the microtensile bond strength of two bonding systems
(2002-01-01)
A laboratory study evaluated the influence of a dentin desensitizer (D/Sense 2) on the microtensile bond strength of two adhesive systems: a self-etching primer (Bistite II SC) and a one-bottle adhesive (Prime & Bond 2.1). ...
Metabolic changes of arachidonic acid in aspirin desensitization [Cambios metabolicos del acido araquidonico en la desensibilizacion a la aspirina]
(1996)
Aspirin sensitivity occurs in 10% of all asthmatic patients. In this subset of asthmatics, nasal congestion and bronchospasm occurs between 30-180 minutes after ingestion of aspirin. Following a respiratory reaction to ...