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Kinetics and reaction mechanism of biothiols involved in SNAr reactions: an experimental study
(Frontiers Media, 2022)
Few kinetic parameters, or reaction rates, are known up to date in detail about 1-chloro and 1-fluoro-2,4-dinitrobenzene (ClDNB and FDNB, respectively) with a series of biothiols in aqueous media. These biological nucleophiles ...
Infection and invasion mechanisms of Trypanosoma cruzi in the congenital transmission of chagas' disease: A proposal
(Society of Biology of Chile, 2010)
Chagas' disease is produced by the haemophlagelated protozoan Trypanosoma cruzi and transmitted by haematophages insects such as Triatoma infestans (vinchuca). Due to vector control, congenital transmission gains importance ...
Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein Stability
(Lippicott Williams & Wilkins, 2015)
Background-L-type calcium channel activity is critical to afterload-induced hypertrophic growth of the heart. However, the mechanisms governing mechanical stress-induced activation of L-type calcium channel activity are ...
Salmonella typhimurium triggers extracellular traps release in murine macrophages
(MDPI, 2021)
Salmonella comprises two species and more than 2500 serovars with marked differences in host specificity, and is responsible for a wide spectrum of diseases, ranging from localized gastroenteritis to severe life-threatening ...
Current Status of Allograft Tolerance in Intestinal Transplantation
(Taylor & Francis, 2014-05)
Solid organ transplantation has become a clinical practice after the development of different immunosuppressive drugs that allowed controlling rejection. The price to be paid for that is the permanent risk of infections ...
A new model to study cell-to-cell transfer of αSynuclein in vivo
(Elsevier B.V., 2018)
© 2018 Elsevier Inc. Parkinson's disease (PD) compromises motor control due to the loss of dopaminergic neurons in the substantia nigra pars compacta. At the histopathological level, PD is characterized by the accumulation ...
Regulation of Connexins Expression Levels by MicroRNAs, an Update
(Frontiers Research Foundation, 2016)
Control of cell-cell coordination and communication is regulated by several factors, including paracrine and autocrine release of biomolecules, and direct exchange of soluble factors between cells through gap junction ...