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The emerging role of TPR-domain immunophilins in the mechanism of action of action of steroid receptors
(AgiAL Publishing Group, 2014-11-30)
In the absence of ligand, some members of nuclear receptor family such as corticosteroid receptors are primarily located in the cytoplasm, and they rapidly accumulate in the nucleus upon ligand-binding. Other members of ...
Cellular localization of TWIK-1, a two-pore-domain potassium channel in the rodent inner ear
(Elsevier, 2003)
K+ channels in the inner ear regulate the secretion and homeostasis of K+, i.e. the flux of K+ ions required to ensure good mechanosensory transduction. We studied the expression and cellular localization of TWIK-1 and ...
Differential regulation of the glucocorticoid receptor nucleocytoplasmic shuttling by TPR-domain proteins
(Elsevier Science, 2021-05)
A dimer of the heat-shock protein of 90-kDa (Hsp90) represents the critical core of the chaperone complex associated to the glucocorticoid receptor (GR) oligomer. The C-terminal end of the Hsp90 dimer shapes a functional ...
Visualization of inositol 1,4,5-trisphosphate receptors on the nuclear envelope outer membrane by freeze-drying and rotary shadowing for electron microscopy
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2010)
The receptors for the second messenger InsP(3) comprise a family of closely related ion channels that release Ca(2+) from intracellular stores, most prominently the endoplasmic reticulum and its extension into the nuclear ...
SNAIL expression correlates with the translocation of syndecan-1 intracellular domain into the nucleus in prostate cancer cell lines
(2020)
Zinc finger protein SNAI1 (SNAIL) and zinc finger protein SNAI2 (SLUG) transcription factors promote epithelial-mesenchymal transition, a process through which epithelial cells acquire a mesenchymal phenotype, increasing ...
Chemotactic transduction in biomining microorganismsHYDROMETALLURGYHydrometallurgy
(ELSEVIER SCIENCE BV, 2017)
Kinase partner protein interacts with the LePRK1 and LePRK2 receptor kinases and plays a role in polarized pollen tube growth
(Wiley Blackwell Publishing, Inc, 2005-05)
The pollen-specific receptor kinases LePRK1 and LePRK2 have localization and expression profiles that strongly suggest they play roles in pollen germination and tube growth. To identify downstream components of LePRK ...
Estudio de las interacciones de la dineína con la región citoplásmica de CD155 y con el virión de poliovirus
(2008-09-25)
RESUMEN: Aunque el mecanismo exacto aún es desconocido, se ha propuesto que uno de los medios por medio del cual poliovirus se disemina al el Sistema Nervioso Central (SNC) es través de los nervios periféricos mediante ...