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The cosmetic dye quinoline yellow causes DNA damage in vitro
(Elsevier B.V., 2015-01-01)
Quinoline yellow (QY) is a chinophthalon derivative used in cosmetic compositions for application to the skin, lips, and/or body surface. However, regulatory data about the genotoxicity and/or mutagenicity of this compound ...
Bonefill® block as alternative for bone substitute: A toxicological evaluation
(2018-01-01)
Bone substitutes based on hydroxyapatite (HA) and Bonefill® (BO-inorganic bovine bone) associated with poly(lactic-co-glycolic acid) (PLGA) (HA/PLGA and BO/PLGA) were evaluated concerning cytotoxicity, genotoxicity and ...
Evaluation of cytotoxic, apoptotic, mutagenic, and chemopreventive activities of semi-synthetic esters of gallic acid
(2017-07-01)
Gallic acid and its derivatives are phenolic compounds widely used as food supplements in the form of capsules, liquid extracts, and ointments owing to their good antioxidant properties. Besides, these compounds are potent ...
Nanocomposites based on bacterial cellulose in combination with osteogenic growth peptide for bone repair: cytotoxic, genotoxic and mutagenic evaluations
(2014)
Bacterial cellulose membranes functionalized with hydroxyapatite or collagen with addition or not of osteogenic growth peptides (OGP) or its C-terminal pentapeptide OGP[10-14] were developed for improving bone repair. The ...
Evaluación de la genotoxicidad en trabajadores expuestos a radiaciones ionizantes en centros de diagnóstico de Barranquilla, un estudio piloto
(Ediciones Universidad Simón BolívarFacultad Ciencias Básicas y Biomédicas, 2019)
Las radiaciones ionizantes (RI) con fines diagnósticos y terapéuticos tienen la propiedad de penetrar tejidos, transformar las células o incluso llevarla a muerte celular, por tanto, resulta un factor de riesgo importante ...
Protein Energy-Malnutrition: Does the In Vitro Zinc Sulfate Supplementation Improve Chromosomal Damage Repair?
(Humana Press, 2014-09-28)
Protein-energy malnutrition (PEM) is originated by a cellular imbalance between nutrient/energy supply and body’s demand. Induction of genetic damage by PEM was reported. The purpose of this study was to determine the ...
Avaliação de Danos Genômicos em Pacientes Submetidos à Hemodiálise Após Suplementação Vitamínica
(Universidade Federal do Espírito SantoBRPrograma de Pós-Graduação em BiotecnologiaUFESMestrado em Biotecnologia, 2012-03-02)
A insuficiência renal crônica (IRC) é cada vez mais frequente na população e implica na perda irreversível das funções renais, o que torna necessário um tratamento de terapia renal substitutiva. A mais comum é a hemodiálise ...
Genotoxic and mutagenic effects of erythrosine B, a xanthene food dye, on HepG2 cells
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012)
Erythrosine (ErB) is a xanthene and an US Food and Drug Administration approved dye used in foods, drugs and cosmetics. Although its utilization is permitted, ErB is described as inhibitor of enzymes and protein-protein ...