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Evaluation of different heterologous prime-boost immunization strategies against Babesia bovis using viral vectored and protein-adjuvant vaccines based on a chimeric multi-antigen
(2016)
Protection against the intraerythrocytic bovine parasite Babesia bovis requires both humoral and cellular immune responses. Therefore, tailored combinations of immunogens targeted at both arms of the immune system are ...
Role of inflammasome activation in tumor immunity triggered by immune checkpoint blockers
(Wiley Blackwell Publishing, Inc, 2020-03)
Immune checkpoint blockers improve the overall survival of a limitednumber of patients among different cancers. Identifying pathways thatinfluence the immunological and clinical response to treatment is criticalto improve ...
Comparison of homologous and heterologous prime-boost immunizations combining MVA-vectored and plant-derived VP2 as a strategy against IBDV
(2017-01)
Different immunogens such as subunit, DNA or live viral-vectored vaccines against Infectious Bursal Disease virus (IBDV) have been evaluated in the last years. However, the heterologous prime-boost approach using recombinant ...
Early T follicular helper cell responses and germinal center reactions are associated with viremia control in immunized rhesus macaques
(American Society for Microbiology, 2019)
T follicular helper (T FH ) cells are fundamental in germinal center (GC) maturation and selection of antigen-specific B cells within secondary lymphoid organs. GC-resident T FH cells have been fully characterized in human ...
Oral immunization with recombinant Lactococcus lactis confers protection against respiratory pneumococcal infection
(National Research Council Canada-NRC Research Press, 2008-10-25)
In the present work, we evaluated if oral immunization with the pneumococcal protective protein A (PppA), expressed in the cell wall of Lactococcus lactis (L. lactis PppA+), was able to confer protective immunity against ...
Short-term and long-term antibody response by mice after immunization against Neisseria meningitidis B or diphtheria toxoid
(Associação Brasileira de Divulgação Científica, 2019)
Avaliação do potencial imunogênico e protetor da vacina contra Doença de Chagas pela estratégia “prime-boost” heterólogo DNA/rNTPDase-1Evaluation of the immunogenic and protective potential of the vaccine against Chagas disease by the heterologous prime-boost strategy DNA/rNTPDase-1
(Universidade Federal de Viçosa, 2018)
Vitamin D boosts immune response of macrophages through a regulatory network of microRNAs and mRNAs
(ElsevierInmunovirologíaNueva York, Estados Unidos, 2022)