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Avaliação da expressão da proteína bcl-2 no carcinoma de mama: estudo em punção aspirativa por agulha fina; correlação com grau histológico em espécimes cirúrgicos correspondentes
(Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia, 2014)
The role of the multi-drug resistance 1, p53, b cell lymphoma 2, and bcl 2-associated X genes in the biologic behavior and chemotherapeutic resistance of canine transmissible venereal tumors
(2019-12-01)
Background: Canine transmissible venereal tumors (CTVTs) generally have different cytomorphologic subtypes and phases of progression. Some tumors have variable biologic behavior including a progressive increase in tumor ...
Immunohistochemical expression of p16INK4a and bcl-2 according to HPV type and to the progression of cervical squamous intraepithelial lesions
(2005-04-01)
Inactivation of the cell cycle inhibitor gene p16MTS1 seems to be involved in human papillomavirus (HPV)-related carcinogenesis because E6 and E7 oncoproteins may impair p16INK4a and, indirectly, bcl-2 functions. In this ...
Expressão das proteínas Fas e Bcl-2 sob estímulo da proteína recombinante HmuY de Porphyromonas gingivalis em células mononucleares de sangue periférico (CMSP) de indivíduos portadores de periodontite crônica
(2013-08-14)
A periodontite é uma doença multifatorial causada pela resposta imuno-inflamatória do hospedeiro sob estímulos bacterianos que destroem o periodonto. Este estudo objetivou investigar a expressão in vitro das proteínas Fas ...
CD4(+) T cells downregulate Bcl-2 in germinal centers
(Springer/plenum PublishersNew YorkEUA, 2005)
Effect of Bcl-2 overexpression on mitochondrial structure and function
(Amer Soc Biochemistry Molecular Biology IncBethesdaEUA, 2002)
Bcl-X-L inhibits Bax-induced alterations in mitochondrial respiration and calcium release
(Elsevier B.V., 2008-09-12)
Apoptosis is a natural cell elimination process involved in a number of physiological and pathological events. This process can be regulated by members of the Bcl-2 family. Bax, a pro-apoptotic member of this family, ...