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Inefficient N2-Like Neutrophils Are Promoted by Androgens During Infection
(Frontiers Media S.A., 2018-09)
Neutrophils are major effectors of acute inflammation against infection and tissue damage, with ability to adapt their phenotype according to the microenvironment. Although sex hormones regulate adaptive immune cells, which ...
Histone deacetylase gene expression is regulated by sex chromosome complement in the amygdala of the developing mouse brain
(2020)
Sexual differentiation of the rodent brain depends mainly on the action of androgens secreted by the fetal testis during the perinatal critical period (E17-P10). Recently, the role of genetic factors derived from sex ...
Seasonal Changes and Regulation of the Glucocorticoid Receptor in the Testis of the Toad Rhinella arenarum
(Wiley, 2012-11)
Several studies indicate that wild free‐living vertebrates seasonally regulate plasma glucocorticoids. However, not only glucocorticoids but also the amount of receptors is important in determining biological responses. ...
Fluoxetine-induced androgenic failure impairs the seminiferous tubules integrity and increases ubiquitin carboxyl-terminal hydrolase L1 (UCHL1): Possible androgenic control of UCHL1 in germ cell death?
(Elsevier B.V., 2019-01-01)
The selective serotonin reuptake inhibitor fluoxetine has been used for the treatment of depression. Although sexual disorders have been reported in male patients, few studies have demonstrated the fluoxetine effect on the ...
Can estrogens be considered as key elements of the challenge hypothesis?The case of intrasexual aggression in a cichlid fish
(Pergamon-Elsevier Science Ltd, 2018-10)
Territorial aggression has been widely studied in males and it has been historically suggested that androgens are key mediators of this behavior. However, more recent evidence suggests that it is the aromatization to ...
Primary Xenografts of Human Prostate Tissue as a Model to Study Angiogenesis Induced by Reactive Stroma
(PUBLIC LIBRARY SCIENCE, 2012)
Characterization of the mechanism(s) of androgen-driven human angiogenesis could have significant implications for modeling new forms of anti-angiogenic therapies for CaP and for developing targeted adjuvant therapies to ...
Response to the gonadotropin releasing hormone agonist leuprolide in immature female sheep androgenized in utero
(Sociedad de Biología de Chile, 2005)
Increased Androgen Receptor and Remodeling in the Prostatic Stroma After the Inhibition of 5-Alpha Reductase and Aromatase in Gerbil Ventral Prostate
(Wiley-liss, 2009-12-01)
Prostate require high levels of steroidogenic enzymes such as 5 alpha-reductase (5 alpha-r) and Aromatase (Aro) for the formation of active steroids. Dihydrotestosterone (DHT), the prostate dominant androgen, is converted ...
Androgen and estrogen receptors and co-regulators levels in endometria from patients with polycystic ovarian syndrome with and without endometrial hyperplasia
(2006)
Objective.: To study if the endocrinological status of PCOS women affects the endometrial sensitivity to steroids by evaluating the expression of androgen receptor (AR), estrogen receptor α (ERα), estrogen receptor β (ERβ), ...