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New selective acetylcholinesterase inhibitors designed from natural piperidine alkaloids
(Elsevier B.V., 2005-07-01)
Five new piperidine alkaloids were designed from natural (-)-3-O-acetyl-spectaline and (-)-spectaline that were obtained from the flowers of Senna spectabilis (sin. Cassia spectabilis, Leguminosae). Two semi-synthetic ...
Acetylcholinesterase Inhibitory Pyridine Alkaloids of the Leaves of Senna multijuga
(Amer Chemical Soc, 2010-03-01)
Two unusual pyridine alkaloids, 7'-multijuguinone (1) and 12'-hydroxy-7'-multijuguinone none (2), were isolated front the leaves of Senna multijuga, together with the known flavonoid rutin. The structures of the new alkaloids ...
Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianus
(Soc Brasileira FarmacognosiaJoao PessoaBrazil, 2012)
Acetylcholinesterase-inhibitor hydrolysates obtained from 'in vitro' enzymatic hydrolysis of mannoproteins extracted from different strains of yeasts
(Wiley Blackwell Publishing, Inc, 2016-02)
In vitro inhibitory activity against acetylcholinesterase (AChE) of peptides obtained by enzymatic hydrolysis of mannoproteins extracted from strains of yeasts was investigated. Yeast mannoproteins were extracted from ...
Rapid eye movement sleep deprivation induces an increase in acetylcholinesterase activity in discrete rat brain regions
(Associação Brasileira de Divulgação Científica, 2001-01-01)
Some upper brainstem cholinergic neurons (pedunculopontine and laterodorsal tegmental nuclei) are involved in the generation of rapid eye movement (REM) sleep and project rostrally to the thalamus and caudally to the medulla ...
New selective acetylcholinesterase inhibitors designed from natural piperidine alkaloids
(Elsevier B.V., 2014)
Characterization of Acetylcholinesterase purified from the Lesser Grain Borer, Rhyzopertha dominica (Coleoptera: Bostrichidae)
(Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, 2018)
Acetylcholinesterase activity in the pons and medulla oblongata of rats after chronic electroconvulsive shock
(Associação Brasileira de Divulgação Científica, 1997-10-01)
An imbalance between cholinergic and noradrenergic neurotransmission has been proposed for the etiology of affective disorders. According to this hypothesis, depression would be the result of enhanced cholinergic and reduced ...
Chemical composition, in vitro cytotoxic and anticholinesterase activities of flower extracts of Senna spectabilis var. excelsa and Senna macranthera
(2021-01-01)
In this study, we investigated the phenolic and antioxidant content, cytotoxic, and anticholinesterase activities of flower extracts of Senna spectabilis var. excelsa and Senna macranthera. The antioxidant activities ...
Rapid eye movement (REM) sleep deprivation reduces rat frontal cortex acetylcholinesterase (EC 3.1.1.7) activity
(Assoc Bras Divulg Cientifica, 1997-05-01)
Rapid eye movement (REM) sleep deprivation induces several behavioral changes. Among these, a decrease in yawning behavior produced by low doses of cholinergic agonists is observed which indicates a change in brain cholinergic ...