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The Therapeutic Revolution of Conjugated Polymer Nanoparticles in Photodynamic Therapy and Photodynamic Inactivation
(Nova Science Publishers, 2020)
Compared to traditional anticancer and antimicrobial therapies, photodynamic therapy (PDT) and photodynamic inactivation (PDI) arise as improved treatment tools due to their highly effective, non-invasive and localized ...
Cardiotoxicity of anticancer therapies. Towards the implementation of cardio-oncology units Cardiotoxicidad inducida por tratamientos oncológicos. Fundamentos para la implementación de equipos de Cardio-Oncología
(Sociedad Medica de Santiago, 2018)
© 2018, Sociedad Medica de Santiago. All rights reserved. Recently, we have witnessed major improvements in cancer treatment. Early diagnosis and development of new therapies have reduced cancer-related mortality. However, ...
Effect of berberine associated with photodynamic therapy in cell lines
(2020-12-01)
Cervical cancer is a serious worldwide health problem. In view of the potentially harmful effects of current conventional therapies, photodynamic therapy may be an option as it is a minimally invasive therapy and can promote ...
GSTT1, GSTM1, and GSTP1 polymorphisms and chemotherapy response in locally advanced breast cancer
(Funpec-editoraRibeirao PretoBrasil, 2010)
Exploring Protein-Protein Interactions as Drug Targets for Anti-cancer Therapy with In Silico Workflows
(Humana Press, 2017)
We describe a computational protocol to aid the design of small molecule and peptide drugs that target protein-protein interactions, particularly for anti-cancer therapy. To achieve this goal, we explore multiple strategies, ...
Hyaluronan degrading silica nanoparticles for skin cancer therapy
(Royal Society of Chemistry, 2013-07)
We report the first nanoformulation of Hyaluronidase (Hyal) and its enhanced adjuvant effect over the free enzyme. Hyaluronic acid (HA) degrading enzyme Hyal was immobilized on 250 nm silica nanoparticles (SiNP) maintaining ...
Fragment-Based QSAR and Molecular Modeling Studies on a Series of Discodermolide Analogs as Microtubule-Stabilizing Anticancer Agents
(WILEY-V C H VERLAG GMBH, 2009)
Inhibition of microtubule function is an attractive rational approach to anticancer therapy. Although taxanes are the most prominent among the microtubule-stabilizers, their clinical toxicity, poor pharmacokinetic properties, ...
Supramolecular photosensitizers as improved tools for anticancer and antimicrobial treatments
(Asociación Química Argentina, 2020-12)
La absorción de luz por una molécula llamada fotosensibilizador (PS) en presencia de oxígeno molecular desencadena la generación de especies reactivas de oxígeno (ROS), que en un medio biológico son capaces de degradar las ...
COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study
Background Individuals with cancer, particularly those who are receiving systemic anticancer treatments, have been
postulated to be at increased risk of mortality from COVID-19. This conjecture has considerable effect on ...