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Efectiveness of chlorthalidone/amiloride versus losartan in patients with stage I hypertension and diabetes mellitus: results from the PREVER‑treatment randomized controlled trial
(Universidade Federal de Minas GeraisBrasilHCL - HOSPITAL DAS CLINICASUFMG, 2021)
Objetivos: Comparar a eficácia na redução da pressão arterial (PA) de uma pílula combinada de clortalidona/amilorida com losartan, durante o tratamento inicial da hipertensão JNC 7 Estágio I em pacientes com diabetes ...
A comparison between diuretics and angiotensin-receptor blocker agents in patients with stage I hypertension (PREVER-treatment trial): Study protocol for a randomized double-blind controlled trial
(2011-02-24)
Background: Cardiovascular disease is the leading cause of death in Brazil, and hypertension is its major risk factor. The benefit of its drug treatment to prevent major cardiovascular events was consistently demonstrated. ...
A comparison between diuretics and angiotensin-receptor blocker agents in patients with stage I hypertension (PREVER-treatment trial): Study protocol for a randomized double-blind controlled trial
(2011-02-24)
Background: Cardiovascular disease is the leading cause of death in Brazil, and hypertension is its major risk factor. The benefit of its drug treatment to prevent major cardiovascular events was consistently demonstrated. ...
Epithelial Sodium Channel in a Human Trophoblast Cell Line (BeWo)
(Springer, 2008-06)
The present study was performed to assay sodium currents in BeWo cells. These cells comprise a human trophoblast cell line which displays many of the biochemical and morphological properties similar to those reported for ...
Prevention of hypertension in patients with pre-hypertension: Protocol for the PREVER-prevention trial
(2011-03-05)
Background: Blood pressure (BP) within pre-hypertensive levels confers higher cardiovascular risk and is an intermediate stage for full hypertension, which develops in an annual rate of 7 out of 100 individuals with 40 to ...
Prevention of hypertension in patients with pre-hypertension: Protocol for the PREVER-prevention trial
(2011-03-05)
Background: Blood pressure (BP) within pre-hypertensive levels confers higher cardiovascular risk and is an intermediate stage for full hypertension, which develops in an annual rate of 7 out of 100 individuals with 40 to ...
Modulation of Intracellular pH in Human Ovarian Cancer
(2016)
To sustain tumor growth, the cancer cells need to adapt to low levels of oxygen (i.e., hypoxia) in the tumor tissue and to the tumor-associated acidic microenvironment. In this phenomenon, the activation of the sodium/proton ...
Inhibition of epithelial sodium channel (enac) with amilorideimproves endothelium-derived vasodilation in angiotensin ii(aii)-treated ratsFASEB JOURNALFASEB J
(FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY, 2016)