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Atividade antimicrobiana e efeito sinérgico entre o derivado sintético 4-Hidroxicumarina e anfotericina B frente cepas de Candida albicans
(Universidade Federal do Rio Grande do NorteBrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM BIOLOGIA PARASITÁRIA, 2022)
Avaliação dos efeitos da cumarina e da 4-hidroxi-cumarima e de diferentes associações com a sulfassalazina no modelo de colite induzida por ácido trinitrobenzenosulfônico (TNBS) em ratos
(Universidade Estadual Paulista (Unesp), 2009-10-13)
As cumarinas representam uma importante classe de compostos fenólicos com inúmeras propriedades farmacológicas que incluem inibição da peroxidação lipídica, da geração de ânion superóxido dependente de neutrófilos, da ...
Avaliação dos efeitos da cumarina e da 4-hidroxi-cumarima e de diferentes associações com a sulfassalazina no modelo de colite induzida por ácido trinitrobenzenosulfônico (TNBS) em ratos
(Universidade Estadual Paulista (Unesp), 2009-10-13)
As cumarinas representam uma importante classe de compostos fenólicos com inúmeras propriedades farmacológicas que incluem inibição da peroxidação lipídica, da geração de ânion superóxido dependente de neutrófilos, da ...
Busca de compostos inseticidas: estudo de espécies do gênero Trichilia (Meliaceae)
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Química - PPGQ, 2006-05-15)
This work describes the results of the search for
insecticidal compounds from the Meliaceae family. The samples assayed against
fall armyworm Spodoptera frugiperda were the hexane, methanol and
hydromethanol extracts ...
Total syntheses of gerberinol i and the pterophyllins 2 and 4 using the Casnati-Skattebøl reaction under different conditions
(Royal Society of Chemistry, 2017-08)
The concise and efficient total syntheses of the naturally-occurring coumarin derivatives gerberinol I, and the pterophyllins 2 and 4, from 5-methyl-4-hydroxycoumarin as a common precursor employing different Casnati-Skattebøl ...
Coumarin-based fluorescent probes for dual recognition of copper(ii) and iron(iii) ions and their application in bio-imaging
(MDPI AG, 2014)
Two new coumarin-based "turn-off" fluorescent probes, (E)-3-((3,4-dihydroxybenzylidene)amino)-7-hydroxy-2H-chromen-2-one (BS1) and (E)-3-((2,4-dihydroxybenzylidene)amino)-7-hydroxy-2H-chromen-2-one (BS2), were synthesized ...
New method for the synthesis of chromeno[4,3-b]chromene derivatives via multicomponent reaction promoted by niobium pentachloride
(2017-01-01)
Chromeno[4,3-b]chromene derivatives were synthesized from multicomponent reaction between 4-hydroxycoumarin, aryl aldehyde derivatives and 1,3-cyclohexanedione promoted by niobium pentachloride. This new method is simple, ...
New diterpenes from Azorella spinosa
(2014)
Two new diterpenes,2-acetoxy-13-hydroxy-mulin-11-ene and 2-acetoxy-mulin-11, 13-diene,have been isolated from the aerial parts of Azorella spinosa and their structures determined by spectroscopic and conventional chemical ...
A kinetic study of the main guaco metabolites using syrup formulation and the identification of an alternative route of coumarin metabolism in humans
(Public Library Science, 2015-03-10)
For decades guaco species have been empirically used for the treatment of respiratory diseases. However, studies have shown that the toxic and therapeutic effects of the main guaco metabolites are dose-dependent, and none ...
New coumarins from Pterocaulon polystachyum
(Georg Thieme Verlag Kg, 2001-01)
Aerial parts of Pterocaulon polystachyum from Chaco province, Argentina, afforded the known coumarins ayapin, isoscopoletin, prenyletin, prenyletin methyl ether, virgatenol, obtusinin, 5-methoxy-6,7-methylenedioxycoumarin, ...