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Platinum(II) metal complexes as potential anti-Trypanosoma cruzi agents
(ELSEVIER SCIENCE INC, 2008-05)
In the search for new therapeutic tools against Chagas’ disease (American Trypanosomiasis) two series of new platinum(II) complexes
with bioactive 5-nitrofuryl containing thiosemicarbazones as ligands were synthesized, ...
Synthesis and characterization of new ruthenium complexes with active ligands against Chagas' disease
(Elsevier Science Sa, 2003-02)
Chagas' disease, considered incurable, is a major third world parasitosis that affects millions of people in Latin America. Previous work has shown that ruthenium clotrimazole complexes are more active against Trypanosoma ...
Novel antitrypanosomal agents based on palladium nitrofurylthiosemicarbazone complexes: DNA and redox metabolism as potential therapeutic targets
(AMER CHEMICAL SOC, 2006-06-01)
In the search for new therapeutic tools against American Trypanosomiasis palladium complexes with bioactive nitrofuran-containing thiosemicarbazones as ligands were obtained. Sixteen novel palladium (II) complexes with the ...
New heterobimetallic ferrocenyl derivatives are promising antitrypanosomal agents
(Royal Society of Chemistry, 2019)
In the search for a more effective chemotherapy for the treatment of Chagas' disease and human African trypanosomiasis, caused by Trypanosoma cruzi and Trypanosoma brucei parasites, respectively, the use of organometallic ...
New heterobimetallic ferrocenyl derivatives are promising antitrypanosomal agents
(Royal Society of Chemistry, 2019-04-15)
In the search for a more effective chemotherapy for the treatment of Chagas´ disease and human African trypanosomiasis, caused by Trypanosoma cruzi and Trypanosoma brucei parasites, respectively, the use of organometallic ...
Estudio fisicoquímico y biológico de una serie de complejos metálicos con ligandos bioactivos contra Trypanosoma cruzi y células neoplásicas
(Universidad de Chile, 2016)
Gracias al descubrimiento de las aplicaciones anticancerígenas del cisplatino, el interés por estos compuestos y sus propiedades ha aumentado, dando altas expectativas en la farmacéutica. En esta tesis se propuso que ...
Synthesis, characterization and antimicrobial activity of a pd(ii) complex with a 1,3-diphenylpyrazole-4-carboxaldehyde thiosemicarbazone ligandSíntesis, caracterización y actividad antimicrobial de un complejo de pd(ii) con ligante 1,3-difenilpirazol-4-carboxaldehído tiosemicarbazona
(Universidad de Ciencias Aplicadas y Ambientales U.D.C.A, 2014)