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Effect of simvastatin in the autonomic system is dependent on the increased gain/sensitivity of the baroreceptors
(Wiley PeriodicalsMalden, 2013-08)
A number of mechanisms have been proposed to explain the pleiotropic effect of statin therapy to reduce sympathetic outflow in cardiovascular disease. We tested the hypothesis that statin treatment could improve baroreflex ...
Role of stress and sympathetic innervation in the development of polycystic ovary syndrome
(HUMANA PRESS INC, 2005-12)
This article presents a review of the role of the sympathetic activity in ovarian pathologies affecting reproductive function. We provide a succinct outline of the findings of our group in this area. The participation of ...
Left ventricular adaptation to high altitude: speckle tracking echocardiography in lowlanders, healthy highlanders and highlanders with chronic mountain sickness
(Springer, 2015)
Hypoxic exposure depresses myocardial contractility in vitro, but has been associated with indices of increased cardiac performance in intact animals and in humans, possibly related to sympathetic nervous system activation. ...
Adaptations in autonomic function during exercise training in heart failure
(SPRINGER, 2008)
Although neurohumoral excitation is the hallmark of heart failure (HF), the mechanisms underlying this alteration are not entirely known. Abnormalities in several systems contribute to neurohumoral excitation in HF, including ...
Purinergic and glutamatergic interactions in the hypothalamic paraventricular nucleus modulate sympathetic outflow
(SpringerDordrecht, 2013-09)
P2X receptors are expressed on ventrolateral medulla projecting paraventricular nucleus (PVN) neurons. Here, we investigate the role of adenosine 5′-triphosphate (ATP) in modulating sympathetic nerve activity (SNA) at the ...
Interaction between the retrotrapezoid nucleus and the parafacial respiratory group to regulate active expiration and sympathetic activity in rats
(Amer Physiological Soc, 2018-11-01)
The retrotrapezoid nucleus (RTN) contains chemosensitive cells that distribute CO2-dependent excitatory drive to the respiratory network. This drive facilitates the function of the respiratory central pattern generator ...
Glucose homoeostasis in rats exposed to acute intermittent hypoxia
(2013-09-01)
Aim: Chronic exposure to intermittent hypoxia commonly induces the activation of sympathetic tonus and the disruption of glucose homoeostasis. However, the effects of exposure to acute intermittent hypoxia (AIH) on glucose ...
Glucose homoeostasis in rats exposed to acute intermittent hypoxia
(2013-09-01)
Aim: Chronic exposure to intermittent hypoxia commonly induces the activation of sympathetic tonus and the disruption of glucose homoeostasis. However, the effects of exposure to acute intermittent hypoxia (AIH) on glucose ...
Prenatal metformin treatment improves ovarian function in offspring of obese rats
(BioScientifica Ltd., 2018)
Maternal obesity causes a wide range of impairment in offspring, such as metabolic and reproductive dysfunctions. We previously demonstrated that female offspring of obese rats have increased serum estradiol levels during ...
Partial reversal of conduction slowing during repetitive stimulation of single sympathetic efferents in human skin
(BLACKWELL, 2004-11)
Aims: To describe and identify the function of a class of human C fibre with an unusual response to repetitive electrical stimulation. Other C fibres slow progressively at 2 Hz (type 1), reach a latency plateau (type 2) ...