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A proposed EPR approach to evaluating agonist binding site of a peptide receptor
(Springer, 2008-06-01)
Angiotensin II (Ang II) and its transmembrane AT(1) receptor were selected in order to test an innovative strategy that might allow the assessment of the agonist binding site in the receptor molecule. With the use of the ...
Conformational basis for the biological activity of TOAC-labeled angiotensin II and bradykinin: Electron paramagnetic resonance, circular dichroism, and fluorescence studies
(2004-08-05)
N-Terminally and internally labeled analogues of the hormones angiotensin (AII, DRVYIHPF) and bradykinin (BK, RPPGFSPFR) were synthesized containing the paramagnetic amino acid 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4- ...
Conformational basis for the biological activity of TOAC-labeled angiotensin II and bradykinin: Electron paramagnetic resonance, circular dichroism, and fluorescence studies
(2004-08-05)
N-Terminally and internally labeled analogues of the hormones angiotensin (AII, DRVYIHPF) and bradykinin (BK, RPPGFSPFR) were synthesized containing the paramagnetic amino acid 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4- ...
Biophysical Studies of TOAC Analogs of the Ctx(Ile21)-Ha Antimicrobial Peptide Using Liposomes
(2022-06-01)
Antimicrobial peptides (AMP) are innate components of the defense system of many forms of life, composing the first line of defense from invading pathogens. Among many AMPs described in several databases, the Ctx(Ile21)-Ha ...
CONFORMATIONAL-CHANGES AT MEMBRANES of TARGET-CELLS INDUCED BY PEPTIDE HORMONE ANGIOTENSIN - SPIN LABEL STUDY
(Elsevier B.V., 1974-01-01)