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Phytogrowth-Inhibitory lactones derivatives of Glaucolide B
(De Gruyter, 2017)
Synthesis of novel α-santonin derivatives as potential cytotoxic agents
(European Journal of Medicinal Chemistry, 2017)
In Silico Study of Structural and Geometrical Requirements of Natural Sesquiterpene Lactones with Trypanocidal Activity
(Bentham Science Publishers, 2013-07)
Chagas’ disease, caused by the intracellular protozoan Trypanosoma cruzi, is one of the most serious health problems throughout South America. Despite the progress that has been made in the study of its biochemistry and ...
Assessment of sesquiterpene lactones isolated from Mikania plants species for their potential efficacy against Trypanosoma cruzi and Leishmania sp.
(Public Library of Science, 2017-09)
Four sesquiterpene lactones, mikanolide, deoxymikanolide, dihydromikanolide and scandenolide, were isolated by a bioassay-guided fractionation of Mikania variifolia and Mikania micrantha dichloromethane extracts. Mikanolide ...
Preparation of sesquiterpene lactone derivatives: Cytotoxic activity and selectivity of action
(Molecular Diversity Preservation International, 2019-03)
Cancer is one of the most important causes of death worldwide. Solid tumors represent the great majority of cancers (>90%) and the chemotherapeutic agents used for their treatment are still characterized by variable efficacy ...
Trypanocidal activity of South American Vernonieae (Asteraceae) extracts and its sesquiterpene lactones
(Taylor & Francis Ltd, 2020-03)
Chagas disease is caused by Trypanosoma cruzi and affects the poorest population in the Americas. Fourteen plant extracts and seventeen sesquiterpene lactones from the tribe Vernonieae (Asteraceae), were evaluated for the ...