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Renin-angiotensin-aldosterone system and COVID-19 infection
With the multiplication of COVID-19 severe acute respiratory syndrome cases due to SARS-COV2, some
concerns about angiotensin-converting enzyme 1 (ACE1) inhibitors (ACEi) and angiotensin II type 1
receptor blockers (ARB) ...
Estradiol, acting through ERα, induces endothelial non-classic renin-angiotensin system increasing angiotensin 1-7 production.
(Elsevier Ireland, 2016-02)
Intracellular renin-angiotensin system (RAS) can operate independently of the circulating RAS. Estrogens provide protective effects by modulating the RAS. Our aim was to investigate the effect of estradiol (E2) on angiotensin ...
Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system
(Portland Press Ltd, 2014)
Chronic RAS (renin-angiotensin system) activation by both AngII (angiotensin II) and aldosterone leads to hypertension and perpetuates a cascade of pro-hypertrophic, pro-inflammatory, pro-thrombotic and atherogenic effects ...
A potential pathophysiological role for galectins and the renin-angiotensin system in preeclampsia
(Springer, 2015-01)
This review discusses a potential role of galectins and the renin-angiotensin system (RAS) in the pathophysiology of preeclampsia (PE). Preeclampsia affects between 3 and 5 % of all pregnancies and is a heterogeneous ...
Prorenins activation by an enzyme from rat plasma (PreR-Co)
(Elsevier Science Inc, 2002-12)
The aim of the present research was to explore the capacity of PreR-Co to process prorenin purified from kidney and corpora lutea (CL) and to study its action on extrarenal tissues. The PreR-Co was obtained from plasma as ...
Characterization of a Local Renin-Angiotensin System in Rat Gingival Tissue
(Amer Acad Periodontology, 2013)
Role of the renin-angiotensin system in the development of severe COVID-19 in hypertensive patients
(American Physiological Society, 2021)