Buscar
Mostrando ítems 31-40 de 602
Design and synthesis of angucyclinone ab-pyrido[2,3-d] pyrimidine analogues
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Emergence of pyridoxal phosphorylation through a promiscuous ancestor during the evolution of hydroxymethyl pyrimidine kinases
(ELSEVIER SCIENCE PUBLISHERS B.V., 2014)
Role of pyrimidine biosynthesis during planarian regeneration
(UniandesBiologíaFacultad de CienciasDepartamento de Biología, 2013)
Synthesis of pyrazolo[1,5-a]pyrimidines in the reaction of 5-amino- 3-arylpyrazoles with methoxymethylene meldrum's acid derivatives and thermolysis of their pyrazolylaminomethylene derivatives
(HeteroCorporation, 1998)
A series of pyrazolo[1,5-a]pyrimidin-3-ones 3 was prepared from Meldrum's acid and 5-amino-3-arylpyrazoles 1 by cyclization in nitrobenzene of the corresponding 5-pyrazolylaminomethylene Meldrum's acid derivatives 2. The ...
Reações de β-enaminodicetonas com ncn dinucleófilos: obtenção de pirimidinas e sistemas heterocíclicos fundidos
(Universidade Federal de Santa MariaBRQuímicaUFSMPrograma de Pós-Graduação em Química, 2016-08-26)
In this study the reactivity of β-enamino diketones [RC(O)C(=CHNMe2)C(O)CO2Et, R = C6H5, 4-Me-C6H4, 4-MeO-C6H4, 4-F-C6H4, 4-Br-C6H4, 4-NO2-C6H4, tien-2-il] with NCN bisnucleophiles as amidine and guanidine was investigated. ...
Estrutura Molecular e Supramolecular de Pirazolo[1,5- a]pirimidinas
(Universidade Federal de Santa MariaBRQuímicaUFSMPrograma de Pós-Graduação em Química, 2010-05-07)
This work describes the molecular and supramolecular structure of fourteen pyrazolo[1,5-a]pyrimidines from bond lengths, torsion angles, angles between planes and interatomic distances. The data discussed were originated ...
Design of new quinolin-2-one-pyrimidine hybrids as sphingosine kinases inhibitors
(Academic Press Inc Elsevier Science, 2020-01)
Sphingosine-1-phosphate is now emerging as an important player in cancer, inflammation, autoimmune, neurological and cardiovascular disorders. Abundance evidence in animal and humans cancer models has shown that SphK1 is ...