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Oral-specific ablation of Klf4 disrupts epithelial terminal differentiation and increases premalignant lesions and carcinomas upon chemical carcinogenesis
(Wiley Blackwell Publishing, Inc, 2015-11)
Background: Squamous cell carcinoma (SSC) of the head and neck is the sixth most common cancer and is rarely diagnosed in early stages. The transcription factor Krvppel-like factor 4 (Klf4) suppresses cell proliferation ...
Ductal epithelial lesions and pancreatic adenocarcinoma
(1990)
Epithelial alterations in pancreatic ducts may have a premalignant nature. We compared the incidence of different lesions in 49 pancreatic cancer specimens compared to 100 controls. Simple hyperplasia, mucosecretory ...
Photodynamic therapy in actinic cheilitis: clinical and anatomopathological evaluation of 19 patients
(SOC BRASILEIRA DERMATOLOGIARIO DE JANEIRO, 2012-05)
BACKGROUND: Actinic cheilitis, a common disease caused by chronic solar exposure and tobacco use, is considered a premalignant lesion with potential to develop into squamous cell carcinoma. Some of the available treatments ...
Angiogenesis in potentially malignant lesions and carcinomas during experimental oral carcinogenesis: a preliminary study in the hamster cheek pouch
(Int Inst Anticancer Research, 2014-11)
AIM: To evaluate vascular morphology and density, angiogenic switch activation, vascular endothelial growth factor (VEGF) expression, and endothelial cell (EC) proliferation in the hamster cheek pouch (HCP) model of oral ...
Estudo das alterações celulares sugestivas de malignidade no líquen plano bucal
(Universidade Estadual Paulista (Unesp), 2006-07-18)
Ainda hoje muito se discute a respeito da natureza pré-maligna do líquen plano bucal. Neste contexto, o presente trabalho tem como objetivo analisar os tipos e o número de alterações celulares sugestivas de malignidade no ...
Análise comparativa da imunoexpressão das proteínas hmlh1 e hmsh2 em carcinomas epidermóides de lábio inferior e queilites actínicas com graus variados de displasia
(Universidade Federal do Rio Grande do NorteBRUFRNPrograma de Pós-Graduação em Patologia OralOdontologia, 2011-12-09)
Lip squamous cell carcinoma (SCC) may develop from a premalignant condition,
actinic cheilitis (AC) in 95% of the cases. Both premalignant and neoplastic lip diseases are
caused mainly by chronic exposure to the ultraviolet ...
Estudo das alterações celulares sugestivas de malignidade no líquen plano bucal
(Universidade Estadual Paulista (Unesp), 2006-07-18)
Ainda hoje muito se discute a respeito da natureza pré-maligna do líquen plano bucal. Neste contexto, o presente trabalho tem como objetivo analisar os tipos e o número de alterações celulares sugestivas de malignidade no ...
Expression of nonclassical molecule human leukocyte antigen-G in oral lesions
(W B Saunders Co-elsevier Inc, 2014)
Estudo das alterações celulares sugestivas de malignidade no líquen plano bucal
(Universidade Estadual Paulista (UNESP), 2014)