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Pentamidine exerts in vitro and in vivo anti Trypanosoma cruzi activity and inhibits the polyamine transport in Trypanosoma cruzi
(Elsevier, 2014)
Pentamidine is an antiprotozoal and fungicide drug used in the treatment of leishmaniasis and African trypanosomiasis. Despite its extensive use as antiparasitic drug, little evidence exists about the effect of pentamidine ...
Key proteins in the polyamine-trypanothione pathway as drug targets against Trypanosoma cruzi
(Bentham Science Publishers B.V., 2014)
In trypanosomatids, redox homeostasis is centered on trypanothione (N 1,N8-bis(glutathionyl)spermidine, T(SH)2), a low molecular weight thiol that is distinctive for this taxonomic family and not present in the mammalian ...
Role of Polyamines in Parasite Cell Architecture and Function
(Bentham Science Publishers, 2018)
Espermidina e espermina exogena na micropropagação de Aloe vera (L.) Burm
(2007-04-01)
The lateral shoots of the Aloe vera L. Burm have been inoculated in culture medium. The work has been divided in two phases. In the phase I different concentrations of NAA and BAP were added to the MS . In the phase II, ...
Ethylene and polyamine production patterns during in vitro shoot organogenesis of two passion fruit species as affected by polyamines and their inhibitor
(SPRINGER, 2009)
Levels of ethylene and polyamines (PAs) were measured during organogenesis of hypocotyl explants of two species of passion fruit (Passiflora cincinnata Masters and Passiflora edulis Sims f. flavicarpa Degener `FB-100`) to ...
Polyamines and related nitrogen compounds in the chemotherapy of neglected diseases caused by kinetoplastids
(Bentham Science Publishers, 2018-05)
Neglected diseases due to the parasitic protozoa Leishmania and Trypanosoma (kinetoplastids) affect millions of people worldwide, and the lack of suitable treatments has promoted an ongoing drug discovery effort to identify ...
Multitasking polyamine/ferrioxalate nano-sized assemblies: thermo-, photo-, and redox-responsive soft materials made easy
(Royal Society of Chemistry, 2019-11)
Responsive nanomaterials have emerged as key components in materials sciences. Herein, we report the one-step preparation of multi-stimuli responsive polyamine-salt aggregates (PSA) by ionically crosslinking polyethylenimine ...