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Ex vivo penetration of fosfomycin into healthy and Lawsonia intracellularis- colonized swine intestinal mucosa
(Wiley Blackwell Publishing, Inc, 2018-07)
Fosfomycin (FOS) is an antibiotic (ATB) used for the treatment of lung and enteric infections of pigs. Intracellular fluids of enterocytes can act as biophase for Lawsonia intracellularis (LAW), causative agent of porcine ...
Fosfomycin protects intestinal cells from nuclear changes suggestive of deoxynivalenol-induced apoptosis
(Wolters Kluwer Medknow Publications, 2020-10)
Background: Fosfomycin (FOS) is a broad-spectrum antibiotic that inhibits cell wall synthesis. It has bactericidal activity against both gram-positive and gram-negative bacteria. FOS also promotes phagocytosis, has ...
Effect of fosfomycin, Cynara scolymus extract, deoxynivalenol and their combinations on intestinal health of weaned piglets
(Elsevier, 2019-08)
Weaning is a challenging stage of pig farming. Animals undergo environmental, social and dietary changes leading to weaning stress syndrome. In order to compensate for the detrimental effects of weaning stress, antibiotics ...
Effect of antibiotics on cellular stress generated in Shiga toxin-producing Escherichia coli O157:H7 and non-O157 biofilms
(Elsevier, 2015-06)
Shiga toxin-producing Escherichia coli (STEC) are important food-borne pathogens, with the main virulence factor of this bacterium being its capacity to secrete Shiga toxins (Stxs). Therefore, the use of certain antibiotics ...
Old antibiotics for multidrug-resistant pathogens: from in vitro activity to clinical outcomes
(Elsevier Science Bv, 2017)
Antimicrobial resistance is a major and emerging threat worldwide. New antimicrobials have been unable to meet the resistance challenge, and treatment options are limited for a growing number of resistant pathogens. More ...