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The dead core model applied to beads with immobilized cells in a fed-batch cephalosporin C production bioprocess
(Elsevier B.V., 2001-01-01)
Viable cells immobilized in inert supports are currently studied for a wide range of bioprocesses. The intrinsic advantages of such systems over suspended cultures incite new research, including studies on fundamental ...
Interaction between the production of ethanol and glycerol in fed-batch bioreactors
(2019-04-01)
During alcoholic fermentation, most of the substrates supplied to the yeasts are converted into ethanol and carbon dioxide generating energy for cell maintenance. However, some of these substrates end up being diverted to ...
Design of dynamic experiments in modeling for optimization of batch processes
(American Chemical Society, 2009-03)
Finding optimal operating conditions fast with a scarce budget of experimental runs is a key problem to speeding up the development of innovative products and processes. Modeling for optimization is proposed as a systematic ...
Dynamic optimization of bioreactors using probabilistic tendency models and Bayesian active learning
(Pergamon-Elsevier Science Ltd, 2013-01)
Due to the complexity of metabolic regulation, first-principles models of bioreactor dynamics typically have built-in errors (structural and parametric uncertainty) which give rise to the need for obtaining relevant data ...
Operation of a fixed-bed bioreactor in batch and fed-batch modes for production of inulinase by solid-state fermentation
(Elsevier Science SaLausanneSuíça, 2011)
Goal-directed Design of Dynamic Experiments for Cybernetic Models of Bioreactors
(Elsevier B.V., 2018-01)
The distinctive feature of cybernetic models of bioreactors is their capacity to account for regulatory mechanisms in a cell metabolism by modeling the synthesis of enzymes and their activities. From a process engineering ...
Estudo da produção de etanol de sacarose por fermentação extrativa utilizando arraste com dióxido de carbono
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Engenharia Química - PPGEQCâmpus São Carlos, 2016-04-18)
The ethanol accumulated in the broth during fermentation is the main component toxic to
yeast, causing slower yeast growth and decreased ethanol production. One way of overcoming
this inhibition effect is to use extractive ...
Diferentes parâmetros de produção de goma xantana pela fermentação de Xanthomonas campestris pv campestris
(Universidade Estadual Paulista (Unesp), 2009-10-01)
A goma xantana é um biopolímero produzido por Xanthomonas campestris muito utilizado como agente espessante. A síntese do biopolímero pode ocorrer em variadas condições, no entanto a qualidade a goma produzida também muda. ...