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Protective effects of curcumin against ischemia-reperfusion injury in the liver
(Academic Press, 2019)
L-Type Calcium Channels Modulation by Estradiol
(Humana Press Inc., 2017)
“Chameleonic” backbone hydrogen bonds in protein binding and as drug targets
(Springer, 2015-10-19)
We carry out a time-averaged contact matrix study to reveal the existence of protein backbone hydrogen bonds (BHBs) whose net persistence in time differs markedly form their corresponding PDB-reported state. We term such ...
LaRbp38: A Leishmania amazonensis protein that binds nuclear and kinetoplast DNAs
(Elsevier B.V., 2007-07-06)
Leishmania amazonensis causes a wide spectrum of leishmaniasis. There are no vaccines or adequate treatment for leishmaniasis, therefore there is considerable interest in the identification of new targets for anti-leishmania ...
LaRbp38: A Leishmania amazonensis protein that binds nuclear and kinetoplast DNAs
(Elsevier B.V., 2007-07-06)
Leishmania amazonensis causes a wide spectrum of leishmaniasis. There are no vaccines or adequate treatment for leishmaniasis, therefore there is considerable interest in the identification of new targets for anti-leishmania ...
Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine
(2005-10-01)
Purine nucleoside phosphorylase (PNP) catalyzes the reversible phosphorolysis of nucleosides and deoxynucleosides, generating ribose 1-phosphate and the purine base, which is an important step of purine catabolism pathway. ...
Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine
(2005-10-01)
Purine nucleoside phosphorylase (PNP) catalyzes the reversible phosphorolysis of nucleosides and deoxynucleosides, generating ribose 1-phosphate and the purine base, which is an important step of purine catabolism pathway. ...
Drug Transporters
(Springer Nature Switzerland AG, 2018)
Membrane transporters perform a central function in many essential body functions, including traffic and compartmentalization of physiologic compounds, absorption of physiologic compounds (and, occasionally, structurally ...
Structural basis of molecular recognition of the Leishmania Small Hydrophilic Endoplasmic Reticulum-associated Protein (SHERP) at membrane surfaces
(Elsevier, 2011)
The 57-residue small hydrophilic endoplasmic reticulum-associated protein (SHERP) shows highly specific, stageregulated expression in the non-replicative vector-transmitted stages of the kinetoplastid parasite, Leishmania ...
Intrinsic disorder associated with 14-3-3 proteins and their partners
(Elsevier, 2019-01)
Protein-protein interactions (PPIs) mediate a variety of cellular processes and form complex networks, where connectivity is achieved owing to the “hub” proteins whose interaction with multiple protein partners is facilitated ...