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proBDNF and p75NTR control excitability and persistent firing of cortical pyramidal neurons
(Society for Neuroscience, 2015-07)
Persistent firing of entorhinal cortex (EC) pyramidal neurons is a key component of working and spatial memory. We report here that a pro-brain-derived neurotrophic factor (proBDNF)-dependent p75NTR signaling pathway plays ...
Effects of somatosensory stimulation on the excitability of the unaffected hemisphere in chronic stroke patients
(Faculdade de Medicina / USP, 2008)
INTRODUCTION: Somatosensory stimulation of the paretic upper limb enhances motor performance and excitability in the affected hemisphere, and increases activity in the unaffected hemisphere, in chronic stroke patients. We ...
Efeitos da estimulação magnética transcraniana repetitiva na modulação da excitabilidade medular e cortical em indivíduos pós-lesão medular incompleta
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Fisioterapia, 2018)
The infralimbic cortical area commands the behavioral and vegetative arousal during appetitive behavior in the rat
(BLACKWELL, 2006-03)
The infralimbic cortical area is a good candidate to send processed motivational signals to initiate the arousing and autonomic responses that characterize appetitive behaviors. To test this hypothesis we enticed hungry ...
Direct mapping rather than motor prediction subserves modulation of corticospinal excitability during observation of actions in real time
(American Physiological Society, 2015-03-25)
Motor facilitation refersto the specific increment in corticospinal excitability (CSE)elicited by the observation of actions performed by others. To date,the precise nature of the mechanism at the basis of this phenomenonis ...
Pumilio-2 regulates translation of Nav1.6 to mediate homeostasis of membrane excitability
(Society For Neuroscience, 2013-06)
The ability to regulate intrinsic membrane excitability, to maintain consistency of action potential firing, is critical for stable neural circuit activity. Without such mechanisms, Hebbian-based synaptic plasticity could ...
Reliable activation of immature neurons in the adult hippocampus
(Public Library of Science, 2009-04)
Neurons born in the adult dentate gyrus develop, mature, and connect over a long interval that can last from six to eight weeks. It has been proposed that, during this period, developing neurons play a relevant role in ...
Estudo da excitabilidade cortical em pacientes com epilepsia mioclônica juvenil com e sem indução por praxia
(Universidade Federal de São Paulo (UNIFESP), 2013-11-27)
INTRODUCTION: The motor patterns of physiological tactile manipulation of objects and voluntary hand movements, defined as praxis, occur through pathways originated from the premotor cortex, primary motor cortex, parietal ...
Cognitive enhancers versus addictive psychostimulants: The good and bad side of dopamine on prefrontal cortical circuits
(Academic Press Ltd - Elsevier Science Ltd, 2016-07)
In this review we describe how highly addictive psychostimulants such as cocaine and methamphetamineactions might underlie hypoexcitabilty in frontal cortical areas observed in clinical and preclinical modelsof psychostimulant ...