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Core 1 O-N-acetylgalactosamine (O-GalNAc) glycosylation in the human cell nucleus
(De Gruyter, 2020-08)
Glycosylation is a very frequent post-translational modification in proteins, and the initiation of O-N-acetylgalactosamine (O-GalNAc) glycosylation has been recently described on relevant nuclear proteins. Here we evaluated ...
Lipopolysaccharide-induced epididymitis modifies the transcriptional profile of Wfdc genes in mice
(Oxford Univ Press Inc, 2021-01-01)
Whey-acidic protein four-disulfide core domain (WFDC) genes display putative roles in innate immunity and fertility. In mice, a locus on chromosome 2 contains 5 and 11 Wfdc genes in its centromeric and telomeric subloci, ...
Biophysical and Dynamic Characterization of Fine-Tuned Binding of the Human Respiratory Syncytial Virus M2-1 Core Domain to Long RNAs
(2020-12-01)
The human respiratory syncytial virus (hRSV) M2-1 protein functions as a processivity and antitermination factor of the viral polymerase complex. Here, the first evidence that the hRSV M2-1 core domain (cdM2-1) alone has ...
Clonagem e expressão da proteína do core do vírus da hepatite C para o desenvolvimento de métodos aplicados ao diagnóstico viral
(Universidade Estadual Paulista (Unesp), 2006-12-08)
O presente trabalho refere-se ao desenvolvimento de duas metodologias: imobilização da proteína do core do vírus da Hepatite C (VHC) em matriz híbrida siloxano-poli (propileno óxido) como suporte sólido para ELISA e um ...
Clonagem e expressão da proteína do core do vírus da hepatite C para o desenvolvimento de métodos aplicados ao diagnóstico viral
(Universidade Estadual Paulista (Unesp), 2006-12-08)
O presente trabalho refere-se ao desenvolvimento de duas metodologias: imobilização da proteína do core do vírus da Hepatite C (VHC) em matriz híbrida siloxano-poli (propileno óxido) como suporte sólido para ELISA e um ...
Protein targets of thiazolidinone derivatives in Toxoplasma gondii and insights into their binding to ROP18 11 Medical and Health Sciences 1108 Medical Microbiology
(BioMed Central, 2018-11)
Background: Thiazolidinone derivatives show inhibitory activity (IC 50 ) against the Toxoplasma gondii parasite, as well as high selectivity with high therapeutic index. To disclose the target proteins of the thiazolidinone ...
Transcription directed by human core promoters with a HomolD box sequence requires DDB1, RECQL and RNA polymerase II machinery
(2012)
TATA box is the most studied core promoter element and has a well-described transcription mechanism. However, most metazoan promoters lack TATA box and contain other core promoter elements. One of such elements is HomolD ...
Expression and spectroscopic analysis of a mutant hepatitis B virus onco-protein HBx without cysteine residues
(Elsevier Science BvAmsterdamHolanda, 2005)
Monoclonal antibodies against Caprine arthritis-encephalitis virus epitopes in the p28 and p55gag viral proteins
(Journal of Virological Methods, 2013)
The genome of the Caprine Arthritis-Encephalitis Virus (CAEV) encodes the polycistronic precursor protein
p55gag. Proteolytic cleavage of p55gag generates the viral core proteins. Some studies suggest that
the CAEV p55gag ...
LaTBP1: A Leishmania amazonensis DNA-binding protein that associates in vivo with telomeres and GT-rich DNA using a Myb-like domain
(Elsevier Science IncNew YorkEUA, 2007)