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Skin Fibroblasts from Patients with Type 1 Diabetes (T1D) Can Be Chemically Transdifferentiated into Insulin-Expressing Clusters: A Transgene-Free Approach
(Public Library of Science, 2014-06)
The conversion of differentiated cells into insulin-producing cells is a promising approach for the autologous replacement of pancreatic cells in patients with type 1 diabetes (T1D). At present, cellular reprogramming ...
A secreted phospholipase A2 induces formation of smooth muscle foam cells which trans-differentiate to macrophage-like state
(2019)
Vascular smooth muscle cells (VSMCs) loaded with lipid droplets (LDs) are markers of
atherosclerosis. In this disease, inflammatory Group IIA-secreted phospholipase A2s (GIIA sPLA2s)
are highly expressed in VSMCs, but ...
Identificación del receptor SV2 isoforma A en cáncer de mama in vitro e in vivo
(2012-04-23)
RESUMEN: Introducción. El cáncer de mama es una enfermedad con índices de prevalencia, incidencia y mortalidad elevados en México y en el mundo. A pesar de ser un grave problema de salud pública, todavía no se conocen la ...
Inhibition of COX 1 and 2 prior to Renal Ischemia/Reperfusion Injury Decreases the Development of Fibrosis
(FEINSTEIN INST MED RESEstados Unidos, 2008)
Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea
(Frontiers Research Foundation, 2015)
Sensorineural hearing loss is most commonly caused by the death of hair cells in the organ of Corti, and once lost, mammalian hair cells do not regenerate. In contrast, other vertebrates such as birds can regenerate hair ...
Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea
(Frontiers Research Foundation, 2015)
Sensorineural hearing loss is most commonly caused by the death of hair cells in the organ of Corti, and once lost, mammalian hair cells do not regenerate. In contrast, other vertebrates such as birds can regenerate hair ...
Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea
(NCBI, 2015)
Sensorineural hearing loss is most commonly caused by the death of hair cells in the organ of Corti, and once lost, mammalian hair cells do not regenerate. In contrast, other vertebrates such as birds can regenerate hair ...
Potencial de transdiferenciação in vitro de células tronco mesenquimais equinas em células schwann-like
(Universidade Estadual Paulista (Unesp), 2022-09-20)
As lesões do sistema nervo periférico (SNP) são condições clínicas comuns que podem desencadear déficits funcionais, afetando a qualidade de vida de humanos e equinos. As lesões do nervo facial são comumente observadas ...
Endothelium trans differentiated from wharton's jelly mesenchymal cells promote tissue regeneration : Potential role of soluble pro-angiogenic factors
(2014-11-20)
Background: Mesenchymal stem cells have a high capacity for trans-differentiation toward many adult cell types, including endothelial cells. Feto-placental tissue, such as Wharton's jelly is a potential source of mesenchymal ...