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Effects of lapatinib on her2-positive and her2-negative canine mammary carcinoma cells cultured in vitro
(2021-06-01)
HER2 is a prognostic and predictive marker widely used in breast cancer. Lapatinib is a tyrosine kinase inhibitor that works by blocking the phosphorylation of the receptor HER2. Its use is related to relatively good results ...
Human breast tumor slices as an alternative approach to cell lines to individualize research for each patient
(Lippincott Williams & Wilkins, 2012-07-01)
There are several breast cancer experimental models including cell lines, which are commonly used due to ease of handling and storage. However, the continued propagation of cell lines and distribution among laboratories ...
Human breast tumor slices as an alternative approach to cell lines to individualize research for each patient
(Lippincott Williams & Wilkins, 2012-07-01)
There are several breast cancer experimental models including cell lines, which are commonly used due to ease of handling and storage. However, the continued propagation of cell lines and distribution among laboratories ...
A cyclized peptide derived from α fetoprotein inhibits the proliferation of ER-positive canine mammary cancer cells
(2009)
The effects of estradiol (E2) and of an AFP-derived cyclized peptide (cP) on the proliferation of primary cultures of cancer cells isolated from spontaneous canine mammary tumors were studied. The cellular response to E2 ...
Daidzein-Estrogen interaction in the rat uterus and its effect on human breast cancer cell growth
(2012)
Sex hormone replacement therapy provides several advantages in the quality of life for climacteric women. However, estrogen-induced cell proliferation in the uterus and mammary gland increases the risk of cancer development ...
Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells
(BioMed Central, 2015)
Background: An increase in circulating platelets, or thrombocytosis, is recognized as an independent risk factor of
bad prognosis and metastasis in patients with ovarian cancer; however the complex role of platelets in ...
Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase
(WILEY, 2010)
Recent reports have suggested that statins induce cell death in certain epithelial cancers and that patients taking statins to reduce cholesterol levels possess lower cancer incidence. However, little is known about the ...