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Vascular dysfunction elicited by a cross talk between periaortic adipose tissue and the vascular wall is reversed by pioglitazone
(Wiley Blackwell Publishing, Inc, 2018-06)
Aim: Perivascular adipose tissue (PVAT) is in intimate contact with the vessel wall and extravascular PVAT-derived inflammatory mediators may adversely influence atherosclerotic plaque formation and stability through ...
Sex-specific hemodynamic and non-hemodynamic determinants of aortic root size in hypertensive subjects with left ventricular hypertrophy
(Nature Publishing GroupLondonInglaterra, 2009)
P2X(7) receptor activation amplifies lipopolysaccharide-induced vascular hyporeactivity via interleukin-1 beta release
(AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, 2008)
Lipopolysaccharide (LPS) stimulates cytoplasmic accumulation of pro-interleukin (IL)-1 beta. Activation of P2X(7) receptors stimulates conversion of pro-IL-1 beta into mature IL-1 beta, which is then secreted. Because both ...
Efeitos da exposição aguda ao cloreto de alumínio (AlCl3) sobre a pressão arterial, reatividade vascular e estresse oxidativo em ratos
(Universidade Federal do PampaCampus Uruguaiana, 2016)
Doxycycline ameliorates 2K-1C hypertension-induced vascular dysfunction in rats by attenuating oxidative stress and improving nitric oxide bioavailability
(ACADEMIC PRESS INC ELSEVIER SCIENCESAN DIEGO, 2012-03-31)
Vascular dysfunction associated with two-kidney, one-clip (2K-1C) hypertension may result from both altered matrix metalloproteinase (MMP) activity and higher concentrations of reactive oxygen species (ROS). Doxycycline ...
Endothelial dysfunction and improvement of the angiotensin II-reactivity in hypercholesterolemic rabbits: Role of cyclooxygenase metabolites
(Elsevier Science, 2008-02)
The aim of this paper was to study the effect of high cholesterol diet on endothelial function and vascular reactivity to angiotensin II and to test the role of vasoconstrictor cyclooxygenase metabolites in this experimental ...
Lercanidipine decreases vascular matrix metalloproteinase-2 activity and protects against vascular dysfunction in diabetic rats
(ELSEVIER SCIENCE BV, 2008)
Abnormal matrix metalloproteinases (MMPs) activity causes cardiovascular diseases. Because hyperglycemia increase MMPs activities through increased oxidative stress. we hypothesized that antioxidant effects produced by ...
Exercise training improves relaxation response and SOD-1 expression in aortic and mesenteric rings from high caloric diet-fed rats
(2008)
Abstract
Background
Obesity has been associated with a variety of disease such as type II diabetes mellitus, arterial ...